炉甘石炮制前后成分分析及热稳定性  

Component Analysis and Thermal Stability of Calamine Before and After Processing

作　　者：张杰红[1,2] 施学骄[1,2] 韦正[1,2] 银铃[1,2] 刘友平[1,2] 

机构地区：[1]成都中医药大学,成都611137 [2]中药资源系统研究与开发利用省部共建国家重点实验室培育基地,成都611137

出　　处：《中国实验方剂学杂志》2011年第24期16-18,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：2011年中医药行业科研专项(201007011-10)

摘　　要：目的:对炉甘石炮制前后的主要物相、化学成分、热稳定性进行研究。方法:通过X射线衍射(XRD)对炉甘石的物相进行分析,运用红外分光光度法(IR)和滴定法对炉甘石的化学成分进行分析,运用差热分析对炉甘石的热稳定性进行研究。结果:炉甘石经炮制后主要物相从单斜晶系的Zn5(CO3)2(OH)6转化成六方晶系的ZnO;碳酸根的伸缩振动及弯曲振动明显减弱;氧化锌的质量分数从63.36%增高到82.95%;样品升温至约250℃时放热,当接近315℃左右时热量不再变化。结论:炉甘石的炮制不仅使化学成分发生变化,而且物相也发生变化,差热分析可以规范炉甘石的明煅温度。Objective：To study on main phase,chemical composition,thermal stability of calamine before and after processing.Method：Analyzed phase and chemical composition of calamine X-ray diffraction（XRD）,infrared spectrophotometry（IR） and titration method;studied thermal stability of calamine by differential thermal analysis.Result： Main phase of calamine after processing changed from monoclinic system of Zn5（CO3）2（OH）6 to hexagonal system of ZnO;Stretching vibration and bending of carbonate obviously weaked;The content of zinc oxide increased from 63.36% to 82.95%;Sample released heat when heated to about 250 ℃ and heat did not change when heated close to 315 ℃.Conclusion： Not only main phase changed of calamine after processing,but also chemical composition changed.Differential thermal analysis（DTA） could regulate calcined temperature of calamine.

关 键 词：炉甘石 炮制 成分分析 热稳定性 

分 类 号：R283.6[医药卫生—中药学]