刺楸树皮的化学成分  

Chemical Constituents from Kalopanax septemlobus

作　　者：范艳君[1] 程东岩[2] 王隶书[2] 

机构地区：[1]长春中医药大学,长春130117 [2]吉林省中医药科学院,长春130012

出　　处：《中国实验方剂学杂志》2011年第24期92-96,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家科技支撑计划(2007BAI38B05)

摘　　要：目的:研究刺楸树皮的化学成分,为阐明其活性成分提供依据。方法:采用80%乙醇进行提取,硅胶柱色谱、ODS柱色谱及高效液相制备进行分离纯化,波谱分析(核磁共振氢谱、碳谱和质谱)确定结构。结果:分离鉴定了7个化合物,分别为3-O-α-L-阿拉伯糖-28-O-α-L-鼠李糖-(1→4)-O-β-D-葡萄糖-(1→6)-O-β-D-葡萄糖基-常春藤皂苷元酯(Ⅰ),刺楸皂苷I(Ⅱ),3-O-α-L-鼠李糖-(1→2)-O-α-L-阿拉伯糖-28-O-β-D-葡萄糖-(1→6)-O-β-D-葡萄糖常春藤皂苷元酯(Ⅲ),刺楸皂苷B(Ⅳ),丁香树脂醇双葡萄糖苷(Ⅴ),2-甲氧基对苯二酚4-O-[6-O-(4-O-α-L-鼠李糖基)-紫丁香基]-β-D-吡喃葡萄糖(Ⅵ),紫丁香苷(Ⅶ)。结论:化合物Ⅰ,Ⅲ,Ⅴ,Ⅵ为首次从本属植物中分得。Objective： To study the chemical constituents from Kalopanax septemlobus and to obtain a more understanding of its active principles.Method： Compounds were extracted with 80% ethanol and isolated by column chromatography on silica gel,ODS and prepared with HPLC;the structures were identified by spectroscopic analysis（1H NMR,13C NMR and EIMS）.Result： Seven compounds were obtained and identified as 3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-（1→4）-O-β-D-glucopyranosyl-（1→6）-O-β-D-glucopyranosyl ester of hederagenin（Ⅰ）,kalopanaxsaponin I（Ⅱ）,3-O-α-L-rhamnopyranosyl-（1→2）-O-α-L-arabinopyranoside-28-O-β-D-glucopyranosyl-（1→6）-O-β-D-glucopyranosyl ester of hederagenin（Ⅲ）,kalopanaxsaponin B（Ⅳ）,liriodendrin（Ⅴ）,2-methoxyhydroquinone 4-O-[6-O-（4-O-α-L-rhamnopyranosyl）-syringyl]-β-D-glucopyranoside（Ⅵ）,syringin（Ⅶ）.Conclusion： Compound Ⅰ,Ⅲ,Ⅴ,Ⅵ were obtained from this cdrus plant for the first time.

关 键 词：刺楸树皮 化学成分 皂苷 

分 类 号：R284.1[医药卫生—中药学]