早期介入栓塞在脑动脉瘤破裂中的治疗效果及预后  

The Efficacy and Prognosis of Early Intervention Treatment in Cerebral Aneurysms Ruptured Treatment

作　　者：黄海鹰[1] 

机构地区：[1]南昌市第一医院脑外科,江西省南昌市330008

出　　处：《中国动脉硬化杂志》2011年第12期1029-1032,共4页Chinese Journal of Arteriosclerosis

摘　　要：目的探究早期介入治疗对脑动脉瘤破裂的疗效以及预后。方法对101例脑动脉瘤患者,均采用介入微弹簧圈栓塞术治疗,其中51例患者在动脉瘤破裂早期(3天)进行介入治疗(早期治疗组),另50例患者为非早期进行介入治疗(对照组)。术后对患者进行随访,改良mRS评分评估疗效。结果早期治疗组患者栓塞疗效明显优于对照组,其mRS评分显著低于对照组(P<0.05)。而组内对比显示,Hunt-Hess分级Ⅳ级以下的患者mRS评分明显低于Ⅳ、Ⅴ级评分的患者(P<0.05)。年龄对比中,年龄≥60岁的患者mRS评分高于<60岁的患者(P<0.05)。中小型动脉瘤患者与大型以及巨大型动脉瘤患者mRS评分差异有显著性(P<0.05)。治疗后并发症发生早期治疗组患者显著低于对照组(P<0.05)。结论早期介入微弹簧圈栓塞治疗脑动脉瘤破裂疗效显著,并能明显降低患者术后相关并发症的发生及有效降低患者动脉瘤再次破裂的机会,提高患者预后。Aim To investigate the efficacy and prognosis of early intervention treatment in cerebral aneurysms ruptured. Methods 101 cerebral aneurysms ruptured patients were selected from April 2007 to February 2011 in our hospital,all patients were treated with interventional micro-coil embolization,including 51 patients with intervene treatment in the early rupture（3 day） as early treatment group,50 patients with non-early interventional treatment as control group.All patients were postoperatively followed-up,with improved mRS score to evaluate the healing effect. Results The healing effect of patients in early treatment group had the significant difference compared with control group（P0.05）,contrast between groups showed that early treatment group＇s mRS score were significantly lower than that of control group（P0.05）.And contrast within the group showed that mRS score of patients under Hunt-Hess grade Ⅳ was significantly lower than the Hunt-Hess grade Ⅳ,Ⅴ patients（P0.05）.Contrast between the age showed age ≥ 60 patient＇s mRS score were higher than age 60 patients（P0.05）.Contrast between the aneurysm size and the treatment effect showed small and medium patient＇s mRS score had significant difference compared with large and huge patients（P0.05）.Early treatment group＇s complication were significantly lower than that in control group（P0.05）. Conclusion Early intervention micro coil embolization in intracranial aneurysm rupture has the remarkable curative effect,and can significantly reduce the incidence of postoperative complications and the chance of aneurysm rupture again,and improve the patients＇ outcomes.

关 键 词：脑动脉瘤 栓塞 微弹簧圈 疗效分析 

分 类 号：R6[医药卫生—外科学]