埋藏式心脏转复除颤器电击治疗的预测因素分析  

Clinical predictors significance of electrical shock in patients with implantable cardioverter defibrillators

作　　者：陆秋芬[1] 李毅刚[1] 俞洁霏[2] 孙健[1] 王群山[1] 

机构地区：[1]上海交通大学医学院附属新华医院心内科,上海200092 [2]上海交通大学医学院附属新华医院老年科,上海200092

出　　处：《中国心脏起搏与心电生理杂志》2011年第6期485-487,共3页Chinese Journal of Cardiac Pacing and Electrophysiology

摘　　要：目的探讨植入埋藏式心脏转复除颤器(ICD)患者电击治疗的预测因素。方法回顾性分析25例植入ICD患者的基础特征,将患者是否进行了ICD治疗分为治疗组和未治疗组,比较两组特征,并采用logistic回归分析电击的预测因素。结果随访18.8±14.3个月后,其中8例共经历21次电击。ICD电击治疗的发生与左室射血分数相关(r=1.129,P=0.030),与年龄、性别、缺血性心脏病、室性心动过速消融、胺碘酮及β受体阻滞剂无相关。多变量COX分析证实左室射血分数(HR 1.08,95%CI 1.07～1.09,P=0.016)是发生电击治疗的独立预测参数。结论严重左室收缩功能障碍的ICD患者容易出现电击治疗。Objective To discuss predicting factors of electrical shock in implantable cardioverter defibrillators （ICD） recipients. Methods Baseline characteristics of 25 ICD recipients were retrospectively analysed. Twenty-five patients were divided into 2 groups ： ICD-treated group and non-ICD-treated group. Compared characteristics between the two groups and found the predictor factors of electrical shock treatment with Logistic regression analysis. Results The mean follow- up was 18.8 ± 14.3 months during which there were 8 patients experiencing a total of 21 episodes of electrical shock. The e- lectrical shock treatment was related with left ventricular ejection fraction （ r = 1. 129, P = 0.030 ）. It had no relationship with age, sex, ischemic heart disease, ablation of ventricular tachycardia, amiodarone, and 13-receptor blocker. Muhivariable Cox analysis confirmed an independent predictive value for left ventricular ejection fraction [ hazard ratio （HR） 1.08, 95% CI 1.07 -1.09, P = 0.016 ]. Conclusion Patients with severe systolic dysfunction are likely to experience electrical shock.

关 键 词：心血管病学 埋藏式心脏转复除颤器 电击 预测因素 

分 类 号：R318.11[医药卫生—生物医学工程]