Collapsed Cone光子束剂量计算方法研究  

Investigation of Photon Dose Calculation Based on Collapsed Cone Algorithm

作　　者：周正东[1] 宋威[1] 

机构地区：[1]南京航空航天大学核科学与工程系,南京210016

出　　处：《中国生物医学工程学报》2011年第6期909-913,共5页Chinese Journal of Biomedical Engineering

基　　金：国家高技术研究发展计划(863计划)(2008AA02Z438);国家自然科学基金(20975052)

摘　　要：剂量计算是放射治疗计划系统的核心,与常用的笔形束剂量计算方法相比,collapsed cone卷积/叠加剂量计算方法具有更高的计算精度,为此我们研究了collapsed cone卷积/叠加剂量计算方法及加速算法,开发了一套基于collapsed cone卷积/叠加剂量计算方法的光子束放射治疗计划系统,并运用蒙特卡罗方法对剂量计算的准确性进行了验证。实验结果表明剂量计算误差与射束能量、射野尺寸以及剂量计算分辨率有关,当天顶角增量和方位角增量分别取3.75°和15°时,对于3～20 cm的方野,剂量计算误差均小于1.5%。所开发的collapsed cone光子束剂量计算方法准确可靠,可望应用于临床。Dose calculation is one of key issues in radiation treatment planning system. Compared with pencil beam algorithm, dose calculation based on collapsed cone algorithm is more accurate and precise. In this paper, dose calculation based on collapsed cone algorithm was investigated, and a photon radiation treatment planning system was developed and accuracy of dose calculation was verified using Monte Carlo method. The experiments showed that the calculated dose precision was related with beam energy, field size and dose calculation resolution, the mean dose error between collapsed cone algorithm and Monte Carlo algorithm was less than 1.5% for square field of 3- 20 cm with the increment zenith and azimuth at 3.75° and 15°. The developed collapsed cone algorithm is promising in the future clinical application for its accuracy and reliablility.

关 键 词：collapsed cone算法 剂量计算 放射治疗计划系统 

分 类 号：TP391[自动化与计算机技术—计算机应用技术] R815[自动化与计算机技术—计算机科学与技术]