闭环复苏技术在失血性休克液体治疗中的应用  

Closed-loop Resuscitation Application in Fluid Therapy of Hemorrhagic Shock

作　　者：赵鹏[1,2] 郑捷文[2] 吴太虎[2] 

机构地区：[1]南方医科大学,广州510515 [2]军事医学科学院卫生装备研究所,天津300161

出　　处：《中国生物医学工程学报》2011年第6期946-954,共9页Chinese Journal of Biomedical Engineering

基　　金：国家高技术研究发展计划(863计划)(2009AA02Z410);国家科技支撑计划(2009BAI79B03)

摘　　要：失血性休克的复苏理论与技术是急救医学、创伤外科学和危重病医学等相关学科研究的焦点。闭环复苏技术以目标血压为复苏终点,通过优化输液"容量"和"速度"制定最佳的治疗方案,在失血性休克治疗的科学研究中应用广泛。文中介绍了当前几种主要的液体复苏闭环控制系统,包括基于PID控制器的线性控制系统,还有基于模糊逻辑、决策支持等智能控制器的非线性控制系统。同时结合现代复苏理论和医学应急救援的发展需求,讨论了闭环复苏技术目前存在的问题和未来发展的趋势。Theories and techniques for resuscitation of hemorrhagic shock are the focus of emergency medicine, trauma surgery and critical care medicine and other related disciplines. Closed-loop resuscitation is widely applied in the research on the treatment of hemorrhagic shock. The closed-loop resuscitation uses blood pressure as target end for resuscitation, by optimizing the infusion ＂ capacity＂ and ＂ velocity＂ to develop the best treatment protocols. This paper described several major closed-loop control systems for fluid resuscitation, including linear control systems based on a PID controller, non-linear control system based on fuzzy logic, and decision-assist intelligent controller. Meanwhile, in combination with the requirements for development of modern theory of fluid resuscitation and the medical aid and emergency treatment, the existing problems and future trends of closed-loop resuscitation were discussed.

关 键 词：闭环控制 液体复苏 失血性休克 

分 类 号：R318[医药卫生—生物医学工程]