肺炎支原体肺炎患儿体液免疫活性的研究  

A Study of humoral immunocompetence in children with mycoplasma pneumonia

作　　者：赵淑琴[1] 崔振泽[2] 蔡栩栩[1] 金婧[1] 尚云晓[1] 吕先科[1] 门永继[1] 张正侯[1] 张英志 

机构地区：[1]沈阳中国医科大学第二临床学院,110003 [2]大连市儿童医院 [3]沈阳医学院附属第二医院

出　　处：《中国实用儿科杂志》1999年第12期728-730,共3页Chinese Journal of Practical Pediatrics

摘　　要：目的　探讨肺炎支原体肺炎（ ＭＰＰ）患儿血清免疫球蛋白（Ｉｇ）、免疫复合物（ＩＣ）和补体（Ｃ）成分含量变化及在发病机制中的作用。方法　采用手动速率散射比浊法和聚乙二醇沉淀比浊法对ＭＰＰ患儿及正常对照组血清ＩｇＧ、ＩｇＡ、ＩｇＭ、ＩＣ和补体Ｃ１ｑ 、Ｃ４ 、Ｃ３ 、Ｂ因子含量进行检测。结果　ＭＰＰ患儿急性期和恢复期血清ＩｇＧ、ＩｇＭ、ＩＣ、Ｃ１ｑ、Ｃ４ 、Ｃ３ 、Ｂ因子含量均明显高于正常对照组（ Ｐ ＜０－０１）。ＭＰＰ重症组血清ＩｇＧ、ＩｇＡ、ＩＣ、Ｃ１ｑ 、Ｃ４ 、Ｃ３ 含量明显高于轻症组（ Ｐ＜ ０－０１ 或＜ ０－０５）。结论　ＭＰＰ患儿体液免疫活性变化在ＭＰＰ发病机制中起重要作用，对判定病情程度有实用价值。Objective To investigate the changes in component of serum immunoglobulin(Ig),immune complex(IC),complement(C)and its effect in pathogenesis in children with mycoplasma pneumonia pneumonia(MPP).Methods The levels of serum IgG,IgA,IgM,IC,andC 1q ,C 4,C 3,B factor were detected in patient with MPP and in normal control group by using turbidity method.Results The levels of serum IgG,IgM,IC and C 1q ,C 4,C 3 in severe group were higher than those in mild group (P<0 01 or <0 05).Conclusion The change of activity of humoral immunity was important in pathogenesis of children with MPP and is valuable in determining the severity of disease. recovered to emmetropia.34.16% of mid high myopia (-3.00D～-6.00D)can be reduced to emmetropia.Conclusion:Orthokeratology is so far the most effective non surgical way of myopia control and reduction.It is important to control myopia in the early stage,so it will not progress to higher myopia. Key words Orthokeratology Reverse geometry Myopia control Corneal curvature Refraction

关 键 词：肺炎支原体 肺炎 免疫球蛋白 补体 儿童 

分 类 号：R725.631[医药卫生—儿科]