增免强力颗粒对小鼠免疫功能影响的研究  

Study on Immune Function in Influence of Zengmian Qiangli Granulas

作　　者：周学愚[1] 吴宗耀[2] 商艳芬[3] 

机构地区：[1]石家庄市第四医院,河北石家庄050000 [2]石家庄市第五医院,河北石家庄050021 [3]石家庄双联化工有限责任公司,河北石家庄050000

出　　处：《中医学报》2011年第12期1469-1470,共2页Acta Chinese Medicine

基　　金：河北省卫生厅计划项目(编号:05215);河北省科技支撑计划项目(编号:07276475);河北省科技攻关计划项目(编号:042761452)

摘　　要：目的:探讨增免强力颗粒治疗小儿反复呼吸道感染的作用机制。方法:以20、15、10 g/kg的剂量给正常小鼠连续7 d灌服增免强力颗粒,观察其对小鼠腹腔巨噬细胞吞噬功能、溶血素及溶血空斑形成的影响。结果:增免强力颗粒可显著提高正常小鼠腹腔巨噬细胞对鸡红细胞的吞噬百分率和吞噬指数;显著促进正常小鼠溶血素的形成,大剂量可显著促进溶血空斑的形成,中、小剂量可明显促进溶血空斑的形成。结论:增免强力颗粒可以明显增强小鼠免疫功能。Objective：To investigate the infection characteristics of Zengmian qiangli granule in treatment of infantile repeated respiratory.Methods：20,15,10 g/kg dose to normal mice for 7 consecutive days.Results：It can significantly increase phagocytic percentage and phagocytic index of the normal mouse peritoneal macrophages in chicken erythrocyte;can significantly promote hemolysin formation of the normal mouse,high dose group can significantly promote the hemolytic plaque formation,middle,small dose could obviously promote the hemolytic plaque formation.Conclusion：Zengmian qiangli particles can significantly enhance the immune function of mice.

关 键 词：增免强力颗粒 免疫功能 小儿反复呼吸道感染 巨噬细胞 溶血素 溶血空斑 吞噬指数 小鼠 

分 类 号：R285[医药卫生—中药学]