左炔诺孕酮宫内缓释系统治疗子宫腺肌病的疗效  

The analysis of effects of levonorgestrel-releasing intrauterine system on 56 women with adenomyosis

作　　者：吴丹梅[1] 金松[1] 

机构地区：[1]海南医学院附属医院妇产科,570102

出　　处：《中国妇产科临床杂志》2011年第6期437-439,共3页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的观察左炔诺孕酮宫内缓释系统(LNG-IUS)治疗子宫腺肌病所致痛经的临床疗效。方法对56例子宫腺肌病所致痛经患者给予放置LNG-IUS治疗。并进行前后自身对照,比较放置前后视觉模拟评分法(VAS)和口述评分法(VRS),以评估痛经和深部性交痛改善情况,并观察月经、子宫大小及副反应情况。结果放置LNG-IUS后3个月,55例(98.2%)患者痛经症状显著缓解或完全消失,月经量显著减少。与放置前比较,放置后3、6、9、12个月VAS和VRS评分明显下降(P<0.01);月经周期和子宫体积差异无统计学意义(P>0.05)。17例(30.4%)深部性交痛患者症状明显缓解;36例(64.3%)贫血患者血红蛋白水平恢复正常。结论 LNG-IUS能有效控制子宫腺肌病患者的疼痛,减少月经量,疗效显著。Objective To evaluate the efficacy and safety of levonorgestrel-releasing intrauterine system（LNG-IUS）for the treatment of dysmenorrheal associated with adenomyosis.Methods 56 cases with moderate or severe dysmenorrheal associated with adenomyosis were treated by LNG-IUS at days 3 to 5 days after menstruation and followed up more than 12 months.Their dysmenorrheal and dyspareunia were scored by the visual analogue scale（VAS）and verbal rating scale（VRS）at baseline and 12 months follow-up.Results Compared with the baseline,VAS and VRS scores of the dysmenorrheal and dyspareunia were decreased significantly after 3 months,6 months,9 months and 12 months of application of LNG-IUS,associated with elevated levels of hematoglobin（P0.01）.There was no significant difference in the menstrual cycle and the uterus size（P0.05）.Conclusions Insertion of LNG-IUS could remarkably alleviates moderate or severe dysmenorrheal associated with adenomyosis.

关 键 词：子宫腺肌病 痛经 深部性交痛 左炔诺孕酮宫内缓释系统 

分 类 号：R711.71[医药卫生—妇产科学]