麻风病临床及病理特点  

Study on clinical characteristics and pathohistological features of leprosy,a report of 9 cases

作　　者：时淑舫[1] 刘金香[1] 周晓鸽[1] 刘健[2] 

机构地区：[1]首都医科大学附属北京友谊医院病理科,北京100050 [2]首都医科大学附属北京友谊医院麻风病研究室,北京100050

出　　处：《临床和实验医学杂志》2011年第24期1891-1893,共3页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨各型麻风病的病理及临床特征,诊断及鉴别诊断,并吸取误诊教训。方法收集皮肤麻风病9例,回顾性分析其临床资料,HE、抗酸染色及病理诊断结果。结果 9例中,根据麻风病的病理分型,表皮出现非浸润带,真皮内是否有神经炎性改变,上皮样肉芽肿或巨噬细胞肉芽肿,淋巴细胞浸润程度,以及抗酸染色,来区分麻风病的病理分型,易误诊,例如皮炎,皮肤病,Poems病及糖尿病皮肤损害,和过敏性疾病。结论麻风病现已少见,有些类型及非典型病例易误诊为皮肤病及其它炎性疾病。Objective To study the pathological features of different clinical types of leprosy,and to discuss their clinical features,diagnosis and differential diagnosis,and to learn lessons from misdiagnosis.Methods The clinical data and pathological diagnosis of biopsy specimens of 9 cases were retrospectively analyzed,and HE staining and acid-fast staining were taken for pathological study.Results Among 9 cases,according to pathological types of leprosy,clear zone,changes of dermal neuritis,epithelioid granuloma or macrophage granuloma,and lymphocyte infiltration were seen in their epidermides,and acid-fast staining was used to distinguish pathological types of leprosy.Leprosy was often misdiagnosed as dermatitis,dermatological diseases,Poems disease and diabetic skin lesions,and allergic diseases.Conclusion Now leprosy is rarely seen,and some types of atypical cases may be misdiagnosed as dermatologic and inflammatory diseases.

关 键 词：麻风病 病理分型 临床病理特征 误诊 

分 类 号：R755[医药卫生—皮肤病学与性病学]