水溶性山药多糖对小鼠的抗衰老作用  

The Antiaging Effects of Water-soluable Polysaccharide from Rhizoma Dioscoreae Opposite on Mice

作　　者：詹彤[1] 陶靖[2] 王淑如[3] 

机构地区：[1]江苏省血液中心,南京210042 [2]解放军第八一医院,南京210002 [3]中国药科大学,南京210024

出　　处：《药学进展》1999年第6期356-360,共5页Progress in Pharmaceutical Sciences

摘　　要：经提取、分离纯化，制备山药多糖精品；并通过腹腔注射山药多糖精品，考察其对小鼠的抗衰老作用。实验结果显示，给药组小鼠体内谷胱甘肽过氧化物酶、过氧化氢酶、超氧化物歧化酶和脑Ｎａ＋ ／Ｋ＋ －ＡＴＰ酶活性均增加；The purified water soluable polysaccharide from Rhizoma Dioscoreae Opposite (RP) was prepared by extraction and separation.And the antiaging effects of the purified RP i.p.on mice were observed. The results showed that the activities of GSH Px in brain and liver, catalase in heart, superoxide dismutase in brain and Na +/K + ATPase in brain were increased and the activity of monoamine oxidase B and the levels of lipid peroxidase and lipofuscin in liver were decreased in RP group.

关 键 词：山药多糖 抗衰老 自由基 小鼠 水溶性 

分 类 号：R285.5[医药卫生—中药学]