生物反应器内搅拌器的优化设计  

Optimization design of stirrer in bioreactor

作　　者：舒安庆[1,2] 刘凯[1] 马长春[3] 魏化中[1,2] 龚哲 董厚生[1] 

机构地区：[1]武汉工程大学机电工程学院,湖北武汉430205 [2]武汉市压力容器压力管道安全技术研究中心,湖北武汉430074 [3]中国通用机械工程总公司,北京100050 [4]湖南智河化工技术设备有限公司,湖南岳阳414000

出　　处：《武汉工程大学学报》2011年第11期66-69,共4页Journal of Wuhan Institute of Technology

摘　　要：简述了生物搅拌器的桨叶型式,利用计算流体力学软件对发酵罐内的流场进行了数值模拟.针对某抗菌素厂发酵罐,直径D=3 800mm,液位高度H=8 600mm,均布4块挡板,转速n=110r/min,上层搅拌器为三层A315搅拌器,原底桨使用Rushton涡轮搅拌器,现改用六叶涡轮搅拌器,对其流场进行了模拟分析比较,结果显示后者有利于罐内发酵液的物质交换,搅拌效果得到改善.The forms of agitator blades were outlined.The flow field in the fermentation tank was simulated by using computational fluid dynamics software.There was a fermenter,diameter D=3 800 mm,liquid height H=8 600 mm,Speed n=110 r/min.A315 turbine agitator was used as up impeller Rushton turbine agitator was used as down impeller.The simulated data shows that the six-leaves turbine stirrer effect is more excellent than Rushton turbine agitator,and much more conducive to the exchange of substances.

关 键 词：生物反应器 发酵罐 搅拌器 数值模拟 

分 类 号：TQ027.2[化学工程]