剖宫产术后应用抗菌药物预防感染与卫生经济学研究  

Antibiotics to prevent infection after cesarean section and health economics research

作　　者：朱宁[1] 刘春红[1] 胡凌云[1] 李丽娜[1] 王良义[1] 

机构地区：[1]解放军总医院门诊妇科,北京100853

出　　处：《中华医院感染学杂志》2011年第24期5261-5262,共2页Chinese Journal of Nosocomiology

摘　　要：目的对剖宫产术后应用抗菌药物预防感染的不同治疗方案,比较抗菌药物应用效果以及卫生经济学价值。方法研究资料按统一的选入和排除标准,选择100例剖宫产产妇,按治疗方案分为甲、乙两组,两组患者均在术前应用头孢替安,甲组于术前、术后6h及术后2d分别壶入头孢替安,共3次,乙组于术后静脉滴注头孢替安,2次/d,共3d6次;比较两组术后3d的最高体温、术后感染率以及抗菌药物的费用。结果甲、乙两组术后1～3d的最高体温比较,差异无统计学意义;甲组47例患者术后3d感染3例,感染率6.38%,乙组53例患者感染4例,感染率7.55%,两组比较,差异无统计学意义;甲组的头孢替安费用为(304.98±0.00)元,乙组的头孢替安费用为(565.84±50.87)元,甲组费用明显低于乙组(P<0.05)。结论择期剖宫产手术如果顺利,可减少抗菌药物应用次数,既可减少抗菌药物的过敏反应,又可减少医务人员的工作量,更重要的是减少了患者的经济负担。OBJECTIVE To compare the effect of antibiotics and value of health economics through the application of antibiotics to prevent infection after cesarean sections is different. METHODS According to the unified standards for selection and exclusion.a total of 100 patients receiving cesarean section were divided into Group A and Group B,both of the two groups used cefotiam before operation.group A took cefotiam by pot for 3 times 6h before and after operation and 2d after operation,and the intravenous infusion of cefotiam was performed for Group B,twice a day,for 3 days;the highest body temperature,the rate of infection after operation,and the cost of antibiotics were compared 3d after operation. RESULTS There was no significant difference in the highest body temperature between the two groups during 1-3 d after operation;the infections occurred in 3 of 47 patients 3d after operation with the rate of infection of 6.38%,the infections occurred in 4 of 53 patients with the rate of infection of 7.55%,there was no significant difference;the cost of cefotiam in Group A was（304.98±0.00）yuan which was significantly lower than（565.84±50.87）yuan in Group B（P＆lt;0.05）. CONCLUSION If the cesarean section is successful,it can reduce the frequency of using antibiotics,the allergic reaction of antibiotics as well as the workload of medical staff,financial burden of the patients in particular.

关 键 词：剖宫产 抗菌药物 体温 术后感染率 

分 类 号：R978.1[医药卫生—药品]