多孔壳聚糖微球/钯催化剂应用于水相Heck反应  

Application of a novel chitosan-base porous microspheres supporting palladium catalyst on Heck reaction in water

作　　者：张鑫[1,2] 王桂艳[1] 曾敏峰[2] 齐陈泽[2] 

机构地区：[1]佳木斯大学药学院,黑龙江佳木斯154007 [2]绍兴文理学院应用化学研究所,浙江绍兴312000

出　　处：《化学试剂》2011年第12期1113-1116,共4页Chemical Reagents

基　　金：浙江省自然科学基金项目(Y4080448;Y4080450)

摘　　要：以与壳聚糖具有一定相容性的水溶性高分子(聚乙二醇)为致孔剂,通过相转变法制得了多孔壳聚糖微球负载钯催化剂。利用扫描电镜、ICP-AES等对催化剂进行了表征。结果表明,所制备的壳聚糖基多孔微球具有高度开放的多孔结构,钯可有效的进入高分子微球的孔道中实现有效负载。该负载型催化剂能较好地催化丙烯酸丁酯与芳基碘系物的水相Heck反应,较高产率(>75%)地生成取代的反式肉桂酸酯。该催化剂易与反应液固-液分离,使用多次后仍具有较好的催化活性。A novel chitosan-base（CS-base） porous microspheres has been prepared by selectively extraction of poly ethylene glycol（PEG） component from CS/PEG semi-IPN microspheres.Palladium can be effectively supported on the obtained CS-base porous microspheres.This heterogeneous catalyst has been characterized by SEM-EDX and ICP-AES.Palladium can easily be fixed on the porous channels of the CS-base microspheres.Such chitosan-base porous microspheres supporting palladium catalyst was an efficient catalyst for Heck reaction of butyl acrylate with aryl iodides in water and obtaining trans-cinnamate with high yield.The catalyst is easy to separate from the reaction system.The supported catalyst remains high activity after used repeatedly for four times.

关 键 词：多孔微球 负载型催化剂 壳聚糖 水相Heck反应 

分 类 号：O621.3[理学—有机化学]