DNA与纳米结构的相互作用及基于力电作用的测序技术  

DNA SEQUENCING METHOD BASED ON ELECTRO-MECHANICAL EFFECTS BETWEEN DNA AND NANO-STRUCTURES

作　　者：李振海[1] 杨卫[2] 

机构地区：[1]清华大学工程力学系,北京100084 [2]浙江大学校长办公室,杭州310058

出　　处：《力学进展》2011年第6期722-729,共8页Advances in Mechanics

摘　　要：本文概述基于力电作用的两类DNA测序技术.这两类测序技术分别依赖DNA与纳米孔或DNA与碳纳米管间的相互作用来实现.文中依次介绍以上两种纳米结构的测序方法,包括:相应纳米结构的制备、与DNA相互作用的表征、测序原理、及各自的研究现状.This review outlines two categories of recent developments in DNA sequencing methods that are based upon electro-mechanical effects. These two methods utilize the interactions between DNA and a nanopore, and between DNA and a carbon nanotube respectively. In this review, we describe the sequencing methods associated with these two nano-structures, including the structure fabrication, the interaction with DNA, the sequencing principle, and the research status.

关 键 词：纳米孔 碳纳米管 DNA测序 

分 类 号：TB383[一般工业技术—材料科学与工程]