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出 处:《畜牧兽医学报》2011年第12期1795-1799,共5页ACTA VETERINARIA ET ZOOTECHNICA SINICA
基 金:广东省科技攻关项目(2007B020707001)
摘 要:本研究旨在探讨日益复杂和多样的J亚群禽白血病的肿瘤病理表现。在流行病学调查基础上,对广东省4个集约型清远麻鸡种鸡场的禽白血病病原进行了分离鉴定和PCR检测,确诊其病原为禽白血病毒J亚群(ALV-J)。通过病理组织学研究发现,这些鸡场ALV-J的主要病理表现为淋巴细胞性肿瘤(82.9%),其次为血管瘤型肿瘤(11.4%),髓细胞性肿瘤仅为5.7%。淋巴细胞性肿瘤主要出现在内脏实质器官,肝脏、脾脏、肾脏、肺脏、腺胃和胰腺等器官明显肿胀,实质中可见大小不一的灰白色肿瘤结节,切面均质柔软。肿瘤的实质主要由典型的成淋巴细胞和淋巴样瘤细胞构成,病理性核分裂像多见。研究结果证实,清远麻鸡出现了一种新的J亚群禽白血病表现形式,即淋巴细胞性J亚群禽白血病,在国内外尚属首次报道。This experiment was conducted to explore the complicated tumor manifestation of avian leucosis subgroup J.On the basis of epidemiology survey of four Qingyuan local layer chicken farms in Guangdong province,then the avian leucosis virus was isolated and detected by PCR test,and avian leucosis virus subgroup J(ALV-J) was definite diagnosed as the pathogen.The histopathologic study showed that the most tumorous manifestation was lymphocytic leucosis(82.9%),and then was hemangioma(11.4%),myeloid leukosis was 5.7%.Abnormal proliferation of lymphocytic leukosis was occurred mainly in parenchymatous organs,including heavy swollen of liver,spleen,kidney,lung,proventriculus and pancreas.There were many ivory-white tumors and nodules occurred in the parenchyma,and the sections were homogeneous and soft.The solid components of tumors were typical lymphoblast and neoplastic lymphoid cells,and many phanerous pathologic nuclear mitotic figures were observed.Those results confirmed that there appeared a novel tumorous manifestation in Qingyuan local chicken,lymphocytic subgroup J-avian leukosis.
关 键 词:成淋巴细胞 淋巴样瘤细胞 ALV-J 病理组织学 清远麻鸡
分 类 号:S852.659.3[农业科学—基础兽医学]
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