睡眠体位、睡眠时相与重度阻塞性睡眠呼吸暂停低通气综合征相关性  

Study of relationship between sleep body posture,sleep phase and severe obstructive sleep apnea-hypopnea syndrome

作　　者：孙玉梅[1] 陈曦[1] 李进让[1] 章榕[1] 

机构地区：[1]海军总医院耳鼻喉科,北京100037

出　　处：《医药论坛杂志》2011年第20期54-56,共3页Journal of Medical Forum

摘　　要：目的研究重度阻塞性睡眠呼吸暂停低通气综合征(severe obstructive sleep apneahypopnea syndrome,SOSAHS)患者呼吸事件的发生与睡眠时相、睡眠体位的关系。方法经多导睡眠监测确诊的61例SOSAHS患者。按是否为体位依赖的OSAHS(仰卧位AHI/非仰卧位AHI≥2)分为2组,即体位依赖(positional patient,PP)组和非体位依赖(nonpositional patient,NPP)组,分别比较各组间年龄、体重指数(BMI)、颈围(NC)、快动眼睡眠期(REM)呼吸暂停低通气指数(AHI)、非快动眼睡眠期(NREM)AHI、最低血氧饱和度(Lowest oxygen saturation,LSaO2)等参数。组内各参数进行相关性分析。结果 PP组BMI明显大于NPP组(t=11.786,P<0.05),而年龄、AHI、LSaO2等参数无明显统计学差异。PP组颈围与呼吸暂停指数(AI)和AHI呈显著正相关(r=0.534,0.536,P<0.05),NREM AHI与AI、AHI和LSaO2呈显著相关性(r=0.758,0.879,-0.484,P<0.05)。结论重度OSAHS患者中,除BMI外体位依赖的OSAHS患者无特殊临床特征,颈围大小影响体位依赖的OSAHS患者病情程度。Objective To study the clinical characteristics and relationship between sleep body posture and occurance of sleep apnea-hypopnea events in patients with severe obstructive sleep apnea-hypopnea syndrome（sOSAHS）.Methods Polysomnography recordings of 61 Patients with sOSAHS were stratified in a group of positional patients（PP）（supine AHI/non-supine AHI ≥ 2） and a group of nonpositional patients（NPP）.The polysomnography data and clinical characteristics were compared between two groups.Results BMI was significantly higher in PP group（t=11.786,P0.05）.In PP groups,neck circumference was significantly correlated with apnea index（AI） and apnea-hypopnea index（AHI）（r=0.534,0.536,P0.05,respectively）.NREM AHI was significantly correlated with AI,AHI and LSaO2（r=0.758,0.879,-0.484,P0.05,respectively）.Conclusions Apart from BMI,no patient characteristics were found indicating the position dependency in patients with sOSAHS.We found significant effects of neck circumference in patients with severe positional OSAHS.

关 键 词：睡眠呼吸暂停低通气 睡眠体位 

分 类 号：R563[医药卫生—呼吸系统]