无创正压通气辅助治疗重症手足口病临床观察  

Effect of noninvasive positive pressure ventilation on the severe cases of hand foot and mouth disease

作　　者：张志英[1] 黄广丽[1] 周红瀛 陈素萍[1] 石庆生[1] 周星[1] 

机构地区：[1]邯郸市妇幼保健院儿科,056001

出　　处：《中国小儿急救医学》2011年第6期529-530,共2页Chinese Pediatric Emergency Medicine

摘　　要：目的探讨无创正压通气辅助治疗重症手足121病的疗效。方法我院2009年4月至2010年8月收治的86例重症手足口病患儿按入院时间分为两组，A组（2009年4月至7月）常规综合治疗38例，B组（2010年4月至8月）常规综合治疗结合经鼻持续气道正压通气辅助治疗48例，比较两组总有效率。结果A组38例，治愈25例，有效6例，无效7例，治愈率65．8％，总有效率81．5％。B组48例，治愈40例，有效7例，无效1例，治愈率83．3％，总有效率97．9％。B组治疗效果显著优于A组，差异有统计学意义（x2=6．71，P〈0．05）。结论重症手足V1病及早使用经鼻持续气道正压通气辅助治疗，对阻止重症病例向危重症发展有重要作用。Objective To evaluate the effects of noninvasive positive pressure ventilation on the se- vere cases of hand foot and mouth disease （HFMD）. Methods Eighty-six cases of severe HFMD admitted to our hospital between Apr 2009 and Aug 2010 were divided into two groups based on the time when admitted to our hospital. Thirty-eight cases （ group A, Apt to Jul, 2009） received routine treatment and 48 cases （group B, Apr to Aug ,2010） were ventilated with nasal continuous positive airway pressure based on routine treatment. The difference of the total efficiency was compared between two groups. Results Twenty-five out of 38 patients were cured, six showed improved signs, and seven showed no improvement in group A, of which the total efficiency was 81.5 %. Forty out of 48 patients were cured, seven showed improved signs, and one showed no improvement in group B, of which the total efficiency was 97.9%. The clinical effect of group B was much better than group A and the difference was statistically significant （X2 = 6.71, P 〈 0. 05 ）. Conclusion Early nasal continuous positive airway pressure has most valuable effect on HFMD and is helpful in preventing HFMD from getting worse.

关 键 词：手足口病 危重症 经鼻持续气道正压通气 

分 类 号：R725.1[医药卫生—儿科]