商丘地区就医人群乙型肝炎血清流行病学研究  

A seroepidemiological study on hepatitis B among patients in shangqiu area

作　　者：王永富[1] 

机构地区：[1]河南省商丘市第一人民医院输血科,476100

出　　处：《中国实用医刊》2011年第24期64-67,共4页Chinese Journal of Practical Medicine

摘　　要：目的了解商丘地区就医人群乙型肝炎（乙肝）病毒（HBV）的感染状况。方法对2009年1月至2010年12月我院就医人群进行问卷调查，并采集血液样本用ELISA酶标法检测HBV感染标志。结果共采集了73518份血液样本，HBsAg、HBsAb、HBeAg、HBeAb、HBcAb流行率及HBV总感染率分别为7．40％、43．30％、1．51％、7．64％、9．20％、38．45％。HBsAg流行率和HBV总感染率在0—5岁、6—12岁、13—18岁、19～60岁、60岁以上人群分别是0．98％和1．03％、2．30％和12．40％、4．49％和16．13％、8．70％和48．71％、8．29％和40．39％。结论商丘地区就医人群中HBsAg流行率在18岁以下人群比19岁以上低，尤其是0—5岁人群，已降低到0．98％；19岁以上人群较高，尤其是长期从事繁重体力劳动人群（农民、搬运工人、建筑工人等）。Objective To acquaintance the serological infection rate of hepatitis B virus（HBV） among.the patients in shangqiu area. Methods From January 2009 to December 2010, a seroepidemio- logical survey was conducted and the samples were collected. Serological biornarkers to hepatitis B virus were tested with enzyme - linked immunosorbent assay （ELISA） reagents. Results Seventy - three thousand five hundred and eighteen samples were collected, the prevalence rates of HBsAg, HBsAb, HBeAg, HBeAb, HBcAb and total HBV infection rate were 7.40% , 43.30% , 1.51% , 7.64% , 9.20% , 38.45%. The positive rates for both HBsAg and HBV infection were 0. 98% and 1.03% under the age of five, 6-12 years old were 2.3% and 12.40%, 13 -18 years old were 4.49% and 16.13% , 19 - 60 years old were 8.70% and 48.00% , over 60 years old were 8.29% and 40. 39%. Conclusions The prevalence rate of HBsAg is lower under the age of 18 than that over 19 years old. The prevalence rate of HBsAg is still high among over 19 years old, especially in long - term engaged in heavy manual work personnel （peasant, builders, stevedore, etc）.

关 键 词：就医人群 乙型肝炎病毒 血清流行病学 流行率 

分 类 号：R512.62[医药卫生—内科学]