静息状态健康成人腓肠肌3.0T^31P-MRS分析  

Analysis of 3.0T 31P-MR spectroscopy：gastrocnemius of healthy adults in the resting state

作　　者：朱凯[1] 由长城[2] 张晓凡 曾立红 刘鹏飞[1] 

机构地区：[1]哈尔滨医科大学附属第一医院MRI科,黑龙江哈尔滨150001 [2]哈尔滨医科大学附属第一医院骨外四科,黑龙江哈尔滨150001 [3]哈尔滨市儿童医院影像科

出　　处：《实用放射学杂志》2011年第12期1869-1872,共4页Journal of Practical Radiology

摘　　要：目的 应用3.0T 31P-MRS对不同年龄组左腓肠肌磷代谢物定量分析,评估其磷代谢物特点,并为腓肠肌31P-MRS检查参数优化提供依据.方法 32例健康志愿者,在静息状态下进行31P-MRS单体素扫描,分别显示7个代谢产物波峰,同时计算pH值、PME/β-ATP、PCr/PME、β-ATP/Pi、PME/Pi、PDE/β-ATP相对定量分析.结果 健康成人静息状态下显示7个代谢物.PME、PCr、Pi、总ATP、PCr/PME、PME/Pi青年组和与老年组有统计学差异.中老年组PME、PME/β-ATP、β-ATP/Pi、PME/Pi、PDE/β-ATP男性与女性有统计学差异.结论 3.0T 31P-MRS可无创量化健康成人不同年龄、各组不同性别静息状态腓肠肌磷代谢产物.Objective To evaluate different age groups of phosphatides metabolism features using 3.0T ^31P-MRS, so that to provide the basis for optimization of ^31 P-MRS examinating gastrocnemius. Methods Single factor ^31 P MRS was carried out at the resting slate in 32 healthy volunteers, 7 metabolites peaks of gastrocnemius, including pH, PME/β ATP, PCr/PME,β-ATP/Pi, PME/Pi and PDE/β-ATP were showed to implement the relative quantitative analysis. Results MRS showed 1hat the PME, PCr, Pi, total ATP,PCr/PME,PME/Pi in the heahhy resting state were significantly different between youth group and the old group. PME, PME/β ATP,β-ATP/Pi, PME/Pi and PDE/βATP were significantly different between men and women in the elderly group. Conclusion 0T β P-MRS can noninvasively quantify the resting gastrocnemius phosphorus metabolites in heahhy adults in different ages and different genders.

关 键 词：31P磁共振波谱 腓肠肌 磷代谢产物 

分 类 号：R445.2[医药卫生—影像医学与核医学] R322.74[医药卫生—诊断学]