具有延时作用的基底膜主动耦合模型  

An active coupling model for basilar membrane with time-delay action

作　　者：王如彬[1] 周轶[1] 张志康[1] 

机构地区：[1]华东理工大学信息学院认知神经动力学研究所,上海200237

出　　处：《振动与冲击》2011年第12期49-53,73,共6页Journal of Vibration and Shock

基　　金：国家自然科学基金项目(10872068;10672057);中央高校基本科研业务费专项资金资助

摘　　要：为了深入理解耳蜗的工作机制,研究了耳蜗中基底膜运动对不同频率和强度分辨能力的影响。针对原有的基底膜振动模型没有考虑外毛细胞在运动过程中由于自身运动所具有的不同速度对基底膜频率响应的影响,使得原有模型无法全面阐述外毛细胞的主动共振作用,为此引入了外毛细胞在增加基底膜频率选择性的机械过程中的延时特性。仿真计算结果表明,修正后的模型完全符合外毛细胞自身作用机制的生理特征。从一个新的角度诠释了外毛细胞运动对基底膜振动作用的贡献。In order to deeply understand working priciple of cochlea, influences of motion of basilar membrane on resolving power for different frequencies and sound pressure levels were studied. Because the original model for vibration of basilar membrane didn＇t consider influences caused by different moving speeds of outer hair cells in the course of their own motion on frequency response of basilar membrane, it could not completely describe active resonance effect of outer hair cells. Therefore, time-delay characteristic of outer hair cells in mechanical process of increasing frequency selectivity of basilar membrane was induced. According to results of simulation calculation, the corrected model absolutely accorded with physiological features of mechanism of action of outer hair cells and it explained the effect of outer hair cells＇ s motion on vibration of basilar membrane.

关 键 词：基底膜运动 外毛细胞 主动耦合性 频率选择性 延时特性 

分 类 号：Q42[生物学—神经生物学]