捻针刺激太溪穴对MCI功能性磁共振成像影响的研究  

Effect of Needle Rotation in Taixi(KI3) Acupoint on Functional MRI in MCI Patients

作　　者：蒋垂刚[1] 崔韶阳[1] 聂彬彬[2] 唐纯志[3] 张家维[3] 

机构地区：[1]广州中医药大学,广州510405 [2]中国科学院高能物理研究所中国科学院核分析技术重点实验室,北京100049 [3]广州中医药大学针灸推拿学院,广州510405

出　　处：《中国中医基础医学杂志》2011年第12期1365-1367,共3页JOURNAL OF BASIC CHINESE MEDICINE

摘　　要：目的:探讨MCI病理状态下针刺太溪穴的脑功能效应中枢机制。方法:纳入MCI患者和健康老年人各12名,针刺右侧太溪穴,实验采用单组块设计,分为针刺前静息态、捻针状态2个模块。扫描后图像使用SPM2进行后处理。结果:针刺前,静息状态、MCI患者组与正常组比较,左侧额上回BA6、左侧扣带回BA24、右侧颞上回BA38血氧代谢降低;针刺太溪穴捻针状态,激活脑区集中于左侧额内侧回BA6、左侧中央后回BA40、左侧岛叶BA13、右侧额内侧回BA6、右侧颞上回BA22、左小脑前叶蚓部。结论:针刺太溪穴靶向性激活了MCI患者病变脑区,且对于相关脑区具有整体性调节效应。Objective： To study the central mechanism of brain function effect with acupuncturing Taixi（KI3） point in MCI pathologic state.Methods： Twelve patients with MCI and twelve normal aging people were enrolled in this research and acupunctured at Taixi points.A block design including two blocks,resting state and rotating state.Scanned images were analyzed by using SPM2.Results： The resting state,group of patients with MCI compared with normal blood oxygen metabolism decreased in left superior frontal gyrus（BA6）,left cingulate gyrus（BA24） and right superior temporal gyrus（BA38）;The medial frontal gyrus（BA6）,left postcentral gyrusBA40,left insula（BA13）,right medial frontal gyrus（BA6）,right superior temporal gyrus（BA22） and left cerebellar culmen were evoked by acupuncture in Taixi.Conclusion： Acupuncture in Taixi（KI3） could activate the target-based brain areas in MCI patients,and had integrity adjustment effect in related brain areas.

关 键 词：针刺 太溪穴 磁共振成像 轻度认知障碍 

分 类 号：R245.9[医药卫生—针灸推拿学]