长托宁与阿托品治疗急性有机磷农药中毒疗效比较  

作　　者：付乐章[1] 

机构地区：[1]四川都江堰市医疗中心,611830

出　　处：《中国社区医师（医学专业）》2011年第34期100-101,共2页

摘　　要：目的:比较长托宁与阿托品治疗急性有机磷农药中毒的疗效。方法:58例急性有机磷农药中毒患者随机分为长托宁治疗组与阿托品对照组,采用推荐剂量按轻、中、重分组并治疗,均用氯磷定,对其疗效进行比较。结果:长托宁治疗组仅发生中间综合症1例,痊愈28例。对照组反跳2例,药物过量5例,痊愈24例。长托宁组的并发症发生率显著低于对照组(P<0.01),达到阿托品化时间无明显差别(P>0.05),尤其给药次数极显著地减少(P<0.001)。结论:长托宁治疗组优于阿托品对照组。Objective：To compare the effect of Penehyclidine Hydrochloride Injection（PHC）and atropine in acute organophosphorus pesticide poisoning.Methods：58 cases of acute organophosphorus pesticide poisoning were randomly divided into treatment group and the PHC atropine control group,using the recommended dose of mild,moderate and severe group to treatment,pralidoxime chloride are used in both group,finally compare its efficacy.Result：In PHC group,28 cases were cured,only 1 case occurred the intermediate syndrome;In control group,2 cases rebound,5 cases occurred drug overdose,24 cases were recovered.The incidence of complications in PHC group was significantly lower than control group（P〈0.01）,to the time of atropine was no significant difference（P〈0.05）,especially,the times of administration significantly reduced（P〈0.001）.Conclusion：PHC group was better in treatment than control group.

关 键 词：急性有机磷农药中毒 阿托品 长托宁 

分 类 号：R595.4[医药卫生—内科学]