武汉地区儿童变应性鼻炎变应原分布特征  

Distribution characteristics of allergens of allergic rhinitis in children in Wuhan region

作　　者：杨柳[1] 段传新[1] 廖大红[1] 黄凌寒[1] 刘志奇[1] 孙文凯[1] 

机构地区：[1]湖北省妇幼保健院,湖北武汉430070

出　　处：《中国妇幼保健》2011年第35期5528-5529,共2页Maternal and Child Health Care of China

摘　　要：目的:探讨武汉市城区儿童变应性鼻炎变应原的分布情况。方法:对2～13岁641例临床诊断为变应性鼻炎的患儿,应用该地区常见的标准化变应原试剂行皮肤点刺试验,对变应原的分布按学龄前及学龄期进行分析。结果:在该地区AR的患儿中,粉尘螨和屋尘螨依然是主要的变应原,其次为艾蒿和霉菌、豚草。变应原总体阳性率排序为粉尘螨(67.13%)、屋尘螨(65.42%)、艾蒿(27.17%)、霉菌Ⅰ(24.96%)、豚草(18.43%)。学龄期儿童较学龄前期儿童变应原的阳性率有增高趋势,以屋尘螨、粉尘螨、豚草阳性率增高显著。结论:尘螨是该地区儿童的最重要的变应原,学龄期儿童较学龄前期儿童的各种变应原的阳性率有增高趋势。Objective：To explore the distributional condition of allergens of allergic rhinitis in urban children in Wuhan city. Methods：641 children aged 2~13 years who were diagnosed as allergic rhinitis clinically received skin prick test through reagents targeting to common and standardized allergens in the region,the distribution of allergens was analyzed in accordance with preschool age and school age. Results：Among the children with allergic rhinitis in the region,dermatophagoides farinae and dermatophagoides pteronyssinus were the main allergens,followed by mugwort,mold and ragweed.The positive rates of dermatophagoides farinae,dermatophagoides pteronyssinus,mugwort,mold mixture Ⅰ and ragweed were 67.13%,65.42%,27.17%,24.96% and 18.43%,respectively.Compared with preschool children,the positive rates of allergens in school children showed a increasing trend,especially the positive rates of dermatophagoides pteronyssinus,dermatophagoides farinae and ragweed. Conclusion：House dust mite is the most important allergen in children in the region;compared with preschool children,the positive rates of various allergens in school children show a increasing trend.

关 键 词：鼻炎 变应性 变应原 

分 类 号：R174[医药卫生—妇幼卫生保健]