微创颅内血肿碎吸术联合依达拉奉治疗高血压脑出血220例  

Minimally Invasive Evacuation Intracranial Hematoma Combined with Edaravone for Treating Hypertensive Cerebral Hemorrhage in 220 Cases

作　　者：冯怡墨[1] 程泽沛[1] 

机构地区：[1]重庆市第三人民医院神经外科,重庆400014

出　　处：《中国药业》2011年第23期65-66,共2页China Pharmaceuticals

摘　　要：目的探讨微创颅内血肿碎吸术联用依达拉奉治疗高血压脑出血的可行性。方法将随机抽取220例高血压脑出血患者分成4组,分别予单独使用一般方法治疗(A组)、微创颅内血肿清除术治疗(B组)、依达拉奉治疗(C组),微创颅内血肿碎吸术联用依达拉奉治疗(D组)。结果治疗14 d后,患者死亡率大小依次为D组(18.18%)、B组(27.27%)、C组(34.55%)、A组(45.45%),且D组治疗1个月后的神经功能缺损程度的改善明显高于其他3组。结论微创颅内血肿碎吸术联用依达拉奉是治疗高血压脑出血是一种安全、有效的方法。Objective To investigate the feasibility of minimally invasive evacuation intracranial hematoma combined with edaravone for treating hypertensive cerebral hemorrhage.Methods Two hundred and twenty patients with hypertensive cerebral hemorrhage were randomly selected and divided into 4 groups,the group D treated by minimally invasive evacuation intracranial hematoma combined with edaravone,the group A treated by common therapy,the group B treated by minimally invasive evacuation intracranial hematoma and the group C by edaravone alone.Results After 14 d treatment,the mortality rates were in turn the group D（18.18%）,the group B（27.27%）,the group C（34.55%） and the group A（45.45%）.Moreover,the improvement of nerve function damage degree after 1-month treatment in the group D was obviously better than that in the other 3 groups.Conclusion Minimally invasive evacuation intracranial hematoma combined with edaravone is a safe and effective method to treat hypertensive cerebral hemorrhage.

关 键 词：微创颅内血肿碎吸术 依达拉奉 高血压脑出血 

分 类 号：R969.4[医药卫生—药理学] R743.34[医药卫生—药学]