儿童单纯疱疹病毒性脑炎11例临床分析  

Analysis of 11 cases of children herpes simplex virus encephalitis

作　　者：陈凤民[1] 邢燕[1] 高丽[1] 

机构地区：[1]河南省人民医院儿科,郑州450003

出　　处：《中国实用神经疾病杂志》2011年第23期23-25,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的分析单纯疱疹病毒性脑炎(HSE)的临床特征、诊断方法及治疗措施。方法对11例HSE患者进行回顾性分析。结果 11例均为急性起病,均有发热、抽搐及意识障碍。其中嗜睡1例,昏迷10例,脑神经损害6例,精神症状3例。神经症状出现最早时间为24h。血清及脑脊液检测HSV-IgM均为阳性,全部病例进行脑电图、头颅CT、MRI检查均显示异常。结论 HSE起病急,惊厥及意识障碍是本病的特征,HSV-IgM阳性是本病确诊的依据,CT、MRI是重要的辅助诊断手段。Objective To analyze the clinical characteristics,diagnosis and treatment method of the herpes simplex virus encephalitis（HSE）.Methods Eleven children HSE were retrospectively analyzed.Results Acute onset accompanied with fever,seizure and consciousness obstruction occurred in all the 11 HSE children.Among them,one case drowsy,10 cases comatose,6 cases with cranial nervous injures,and 3 cases with mental symptom.The earliest nerve symptom appeared at 24 hours since onset.HSV-IgM in the serum and the cranial spinal fluid of all the cases appeared positive.All the cases carried on electroencephalogram,skull CT and MRI inspection,and all displayed some abnormality.Conclusion Acute onset,seizure and unconsciousness are the characteristics of HSE.Positive HSV-IgM is the diagnostic basis of HSE,while,CT and MRI inspection are the important assistance diagnosis way.

关 键 词：儿童 单纯疱疹病毒 病毒性脑炎 

分 类 号：R512.3[医药卫生—内科学]