贮存式自体输血在Rh(D)阴性孕妇分娩中的应用  

Application of predeposit autologous blood transfusion in delivery of Rh(D) negative pregnant women

作　　者：许进明[1] 周小玉[1] 余悦娇[1] 孙云雨[1] 熊婷[1] 

机构地区：[1]南京医科大学第一附属医院输血科,南京210029

出　　处：《临床血液学杂志（输血与检验）》2011年第6期699-701,共3页Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)

摘　　要：目的:了解贮存式自体输血在Rh(D)阴性孕妇分娩中的实际应用情况。方法:产前1～3周采集并贮存孕妇自身血液,分娩时或分娩后回输给产妇。结果:产前45例贮存自体血的Rh(D)阴性孕妇中,有10例在分娩中或分娩后回输了自体血(未输异体血),未见不良输血反应发生,母婴状况良好,Apgar评分多为10分。另外有7例产妇除了回输自体血外,又输注了一定量的异体血。比较采血前后、回输前后、回输与未回输组以及回输自体血与回输自异体血四组血液指标变化情况,均显示差异无统计学意义(P>0.05)。结论:贮存式自体输血在Rh(D)阴性孕妇分娩中是行之有效的输血方式,既解决了血源紧张的问题,尤其是对稀有血型患者,减少异体血的输注,又提高了输血的安全性和合理性,对母婴不会造成危险,值得推广。Objective：To explore the actual application of predeposit autologous blood transfusion in the delivery of Rh（D） negative pregnant women.Method：The pregnant women’s own blood was collected and stored prior to 1-3 weeks of delivery,and then transfused back in or after delivery if necessary.Result：Ten of the 45 Rh（D） negative pregnant women who had participated autologous blood storage before pregnancy received the autologous blood transfusion during or after delivery （allogeneic blood transfusion was avoided）.No adverse transfusion reactions were observed,and both the mothers and newborns were in good condition.Most of the newborns got 10 on Apgar score.There were another 7 cases who also received certain amount of allogeneic blood in addition to autologous blood.Changes in biochemical and hematological parameters of blood were respectively compared before and after the transfusion,between transfusion and non-transfusion group,as well as autologous blood transfusion and homologous blood transfusion group,and no significant differences were found（P0.05）.Conclusion：Predeposit autologous blood transfusion may be an effective transfusion way for Rh（D） negative pregnant women,which might help ease the blood shortage,especially for rare blood types,and reduce the likelihood of allogeneic blood transfusion.Thus,it could enhance the safety and rationality of blood transfusion,and exert no threat to mother and child.Therefore,it is well worth promoting.

关 键 词：贮存式自体输血 RH(D)阴性 孕妇 

分 类 号：R457.1[医药卫生—治疗学]