2型糖尿病伴代谢综合征患者超声心动图的变化  

The Echocardiographical characterics in patients with type 2 diabetes and metabolic syndrome

作　　者：刘波[1] 秦春梅[1] 尹福在[1] 陆强[1] 马春明[1] 吴广飞[1] 王蕊[1] 

机构地区：[1]河北省秦皇岛市第一医院内分泌科,066000

出　　处：《中国综合临床》2011年第12期1297-1300,共4页Clinical Medicine of China

摘　　要：目的评价代谢综合征（MS）对糖尿病患者心室重构存在的影响。方法选取2型糖尿病患者102例，分为非代谢综合征组（DM组）53例和MS组49例。所有研究对象均采用标准方法检测血压、测量身高、体重；检测血糖、血脂等生化指标。采用美国超声心动图协会（ASE）推荐的标准方法测量研究对象的心脏超声相关参数。主要测量舒张期末期左心室内径（LVD）、舒张期末期左心室后壁厚度（LVPW）、舒张期末期室间隔厚度（IVS）以评估左心室结构，计算相关参数。结果MS组与DM组IVS[（9．43±1．41）、（8．57±1．38）mm，t=3．117，P=0．002]、LVPW[（9．12±1．18）、（8．64±1．17）mm，t=2．055，P=0．042]、左心室重量（LVM）[（147．04±34．80）、（127．00±30．11）g，t=3．110，P=0．002]和左心室重量指数（LVMI）[（36．82±8．60）、（32．00±6．81）ks／m2.7，t=3．115，P=0．002]比较差异均有统计学意义。MS组左心室肥厚检出率高于DM组，差异有统计学意义（16．32％与1．89％ x=5．524，P=0．032）。结论合并MS的2型糖尿病患者存在更严重的心脏结构异常，更易发生左心室肥厚。Objective To assess the effects of metabolic symdrome （MS） on the left ventricle remodeling of patients with Diabetes Mellitus （DM） by analyzing the echoeardiographical data. Methods One hundred and two cases with Type 2 Diabetes Mellitus （T2-DM） were selected. According to the diagnostic criteria of MS, they are divided into MS group and non-MS group. All patients were determined for biochemical indicators by fasting venous blood assay. Patients were monitored by Color Doppler echocardiography for left ventricle inner diameter （LVD）, left ventricular posterior wall thickness （LVPW） and interventricular septum thickness （IVS） at the end of diastole period. Left ventricular mass （LVM） were calculated according to Dereveux formula. Results Between MS and non-MS groups, there were significant deference in the value of IVS （ [9.43 ± 1.41 ]mm vs [8. 57 ± 1.38] mm,t =3. 117 ,P =0. 002） ,LVPW（ [9. 12 ± 1.18]mm vs [8. 64 ± 1.17]mm,t =2.055,P =0.042）,LVM（[147.04 ±34. 80]g vs [127.00 ±30. 11]g,t =3. 110,P =0.002） and LVMI （ [ 36. 82 ± 8. 60 ] kg/m2. 7 vs [ 32. 00 ± 6. 81 ] kg/m2.7, t = 3. 115, P = 0. 002）. MS group has the higher values than non-MS group in T2-DM patients （P 〈 0. 05 ）. In MS group, the prevalence of LVH was higher than that in non-MS group （ 16. 32% vs 1.89%, x2 = 5. 524, P = 0. 032）. Conclusion The patients with MS have a severe condition in left ventricle remodeling,indicating that MS played an important role in left ventricle remodeling process.

关 键 词：糖尿病 代谢综合征 心室重构 左心室肥厚 

分 类 号：R589[医药卫生—内分泌]