复方磺胺氯吡嗪钠不同组方与剂型对鸡球虫病的疗效  

Efficacy of different formulations and prescriptions of sulfachloropyrazine sodium compound against chicken coccidiosis

作　　者：钱学智[1] 

机构地区：[1]江苏畜牧兽医职业技术学院,江苏泰州225300

出　　处：《畜牧与兽医》2011年第12期16-19,共4页Animal Husbandry & Veterinary Medicine

摘　　要：通过动物体内试验,比较复方磺胺氯吡嗪钠的不同组方与剂型对鸡球虫病的疗效。第一次试验设磺胺氯吡嗪钠+三甲氧苄啶(TMP)溶液组(0.02%,5 d)、磺胺氯吡嗪钠+TMP混悬液组(0.02%,5 d)、磺胺氯吡嗪钠+二甲氧苄啶(DVD)混悬液组(0.02%,5 d)、药物对照组(磺胺氯吡嗪钠可溶性粉,0.03%,5 d)、感染不用药组和不感染不用药组。第二次试验设磺胺氯吡嗪钠+TMP混悬液组(0.02%,5 d)、磺胺氯吡嗪钠+DVD混悬液组-1(0.02%,5 d)、磺胺氯吡嗪钠+DVD混悬液组-2(0.02%,3 d)、药物对照组(磺胺氯吡嗪钠可溶性粉,0.03%,3d)、感染不用药组和不感染不用药组。每组30只鸡。以血便记分、存活率、增重及相对增重率、病变记分与病变值、卵囊产量与卵囊值、抗球虫指数(ACI)等指标综合评定抗球虫效果。结果显示:磺胺氯吡嗪钠+TMP混悬液组(0.02%,5 d)和磺胺氯吡嗪钠+DVD混悬液组(0.02%,5 d)的抗球虫指数始终大于或接近180,为抗球虫高效水平;磺胺氯吡嗪钠+TMP溶液组(0.02%,5 d)、磺胺氯吡嗪钠+DVD混悬液组(0.02%,3 d)的抗球虫指数大于160,为抗球虫中效水平。提示:磺胺氯吡嗪钠+TMP混悬液(0.02%,5 d)和磺胺氯吡嗪钠+DVD混悬液(0.02%,5 d)对鸡球虫有较好的疗效。The study was designed to evaluate the anticoccidial activity of different formulations and prescriptions of sulfachloropyrazine sodium （Esb3 ） compound against chicken coccidiosis. The two trials were carried out. In the first trial, 180 chickens were divided into six groups： Esb3 with trimethoprin （TMP） solution （0. 02%, 5 d）, Esb3 with TMP suspension （0. 02%, 5 d）, Esb3 with diaveridine （DVD） suspension （0. 02% , 5 d） group, Esb3 soluble powder （0.03% , 5 d）, infected and non-medicated group and uninfected and non-medica- ted group. In the second trial, 180 chickens were similarly divided into six groups： Esb3 with TMP suspension （0. 02% , 5 d）, Esb3 with DVD suspension （0. 02%, 5 d）, Esb3 with DVD suspension （0. 02%, 3 d）, Esb3 soluble powder （0. 03%, 3 d）, infected and non-medicated group and uninfected and non-medicated group. Anticoecidial activity was evaluated by the scores of blood faeces, the survival rate, weight gain and relative weight gain rate, lesions scores, oocysts scores and value of oocysts and anti-eoceidia index （ACI）. The results showed that ACIs in Esb3 with TMP suspension （0. 02%, 5 d） or with DVD suspension （0.02%, 5 d） groupz were kept in high level, and those in Esb3 with TMP solution （0. 02%, 5 d） or with DVD suspension （0.02% , 3 d） groups were kept in middle level. It suggested that Esb3 with TMP or DVD suspension （0.02% , 5 d） had a better efficacy against chicken coccidiosis.

关 键 词：柔嫩艾美耳球虫 磺胺氯吡嗪钠 TMP DVD 效力 

分 类 号：S852.7[农业科学—基础兽医学]