超声心动图联合血浆BNP诊断原发性高血压患者心功能损害  

ECHOCARDIOGRAPHY COMBINED WITH PLASMA BNP IN DIAGNOSIS OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH ESSENTIAL HYPERTENSION

作　　者：李娜[1] 舒晓丹[1] 朱昱思 丁晶[1] 裴峰[1] 

机构地区：[1]武警上海总队医院特检科,上海201103

出　　处：《现代预防医学》2012年第1期217-218,221,共3页Modern Preventive Medicine

摘　　要：[目的]探讨应用超声心动图和血浆B-型钠尿肽(B-type natriuretic peptide,BNP)水平诊断高血压心功能受损。[方法]选择门诊及住院高血压患者150例,将其中心脏超声示左室肥厚、血浆BNP水平≥100 pg/ml者70例归为A组;左室肥厚、血浆BNP﹤100 pg/ml者80例归为B组;另选健康检查50人作对照(C组)。空腹抽血测血浆BNP浓度,心脏彩超检测左室厚度及左室舒张功能。[结果]A、B两组超声心动图显示左室肥厚及左室舒张功能的测值无显著差异,但A、B组显著高于C组(P﹤0.01)。3组间的血浆BNP水平差异显著。[结论超声心动图结合血浆BNP水平能准确判断高血压患者心脏功能受损情况。[Objective]To explore the effect of integration of echocardiographs and plasma B-type natriuretic peptide（BNP）on diagnosis left ventricular diastolic dysfunction of hypertension.[Methods]All the 150 patients were divided into groups.The group A（n = 70）accepted echocardiography showed left ventricular hypertrophy and plasma BNP levels﹥100（pg/ml）.The others（n = 80）accepted echocardiography showed left ventricular hypertrophy and plasma BNP levels was ﹤100（pg/ml）were arranged into group B.Another（n = 50）healthy cases were classified into control group C.[Results]There were no significant difference of the left ventricular hypertrophy and left ventricular diastolic function in group A and B.But the plasma BNP levels were significantly different in group A,B and C（P﹤0.01）.[Conclusion]Echocardiography combined with plasma BNP can more accurately determine left ventricular hypertrophy in patients with essential hypertension.

关 键 词：超声心动图 高血压病 左室功能 B-型钠尿肽 

分 类 号：R544.1[医药卫生—心血管疾病]