无锡地区老年失眠患者苯二氮类药物使用情况分析  

Investigation on outpatient medication of elderly patients with insomnia in Wuxi

作　　者：丁兆生 任宏泉 李佟 

机构地区：[1]江苏省荣军医院,江苏无锡214035

出　　处：《中国民康医学》2011年第24期3021-3022,3029,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:调查了解无锡地区老年失眠患者苯二氮类(BZD)药物使用情况。方法:采用自编调查表调查江苏省荣军医院及无锡市第四人民医院2009年11月～2010年3月因失眠而在门诊就诊的老年患者1 224例,根据限定日剂量(DDD)和药物利用指数(DUI)对BZD等药物的临床使用进行分析。结果:因失眠而就诊的老年人BZD使用频率高达91.83%;BZD合并抗精神病药物及抗抑郁药物占64.22%;两种以上BZD合并使用者占26.72%;艾司唑仑、阿普唑仑、氯硝西泮、硝西泮、地西泮的DUI>1。结论:无锡地区老年人BZD临床使用不尽合理,老年人BZD依赖情况严重,合并用药较多,改变BZD使用模式迫在眉睫。Objective:To investigate outpatient medication of elderly patients with insomnia in Wuxi.Methods:A self-designed questionnaire was used to investigate 1 224 cases of elderly patients who visited hospital because of insomnia.These patients were recruited from Rongjun Hospital of Jiangsu and the Fourth People' s Hospital of Wuxi from November 2009 to March 2010.According to defined daily doses(DDD) and drug use index(DUI),clinical use of drugs such as benzodiazepine(BZD) etc was analyzed.Results:The BZD usage frequency was up to 91.83% in elderly patients who visited hospital due to insomnia;BZD combined with antipsychotic drug and antidepressant drug accounted for 64.22%;merging two or more BZD accounted for 26.72%;the DUI of estazolam,alprazolam,clonazepam,nitrazepam and diazepam was greater than or equal to 1.Conclusion:The clinical use of BZD was unreasonable among elderly people in Wuxi,which had serious dependence and more combined medication.Therefore,it was urgent to change the usage patterns of BZD.

关 键 词：苯二氮类药物(BZD) 限定日剂量(DDD) 药物使用指数(DUI) 失眠 

分 类 号：R971.3[医药卫生—药品]