聚己内酯的应用研究进展  

Advances in application research of polycaprolactone

作　　者：杨延慧[1] 严涵[1] 康晓梅[1] 徐静[1] 陈红[1] 陈晓浪[2] 张志斌[1] 

机构地区：[1]西南交通大学生命科学与工程学院,成都610031 [2]西南交通大学材料科学与工程学院,成都610031

出　　处：《化工新型材料》2011年第12期13-15,45,共4页New Chemical Materials

基　　金：国家自然科学基金资助项目(51003088;50573061);教育部新世纪优秀人才支持计划(NECT-08-0820);中央高校基本科研业务费专项资金资助(2010ZT09;SWJTU09CX062)

摘　　要：综述了聚己内酯的重要特性及在生物医药方面的研究进展,主要介绍了聚己内酯作为药物释放载体、组织工程支架材料等以及其他方面的应用研究。Polycaprolactone was a kind of polyester of fatty acid which had good degradation, drug permeability, non-toxic, good mechanical properties, high elasticity and good biocompatibility. It can be widely used as medicine carrier materials and tissue engineering scaffold material. Polycaprolactone polyol was also used in elastomers, coatings, adhe- sives, etc. Some properties and recently research progress of polycaprolactone in biomedical applications were reviewed. And the research progress of polycaprolactone as the carrier materials of medicine and scaffold materials for tissue engineering and others were introduced.

关 键 词：聚己内酯 药物载体 组织工程材料 聚己内酯多元醇 

分 类 号：R318.08[医药卫生—生物医学工程]