调胃丸药理作用的实验研究  

A Study on Pharmacodynamic Effect of Tiaowei Pill

作　　者：师青春[1] 杨连文[1] 高景泰[1] 杨桂英[1] 张琳[1] 

机构地区：[1]黑龙江省中医研究院,哈尔滨150036

出　　处：《中国中西医结合脾胃杂志》2000年第1期14-16,共3页

摘　　要：目的 :研究调胃丸的治疗机制及药理作用。方法 :采用幽门弹簧扩张法及胃部胆汁与小肠液灌注法引起小鼠的慢性胆汁反流性胃炎和急性胃炎后给予不同剂量调胃丸治疗 ,观察其疗效。结果 :调胃丸能减少小鼠胃粘膜出血点 ,减轻粘膜水肿 ,抑制反流性胃炎的发生率 ,尤以大剂量作用明显 ,与模型组比较有极显著性差异 (P <0 .0 1) ;并对醋酸引起的小鼠扭体反应有一定的抑制作用。结论 :调胃丸有一定的镇痛作用 ,对急、慢性反流性胃炎均有一定的保护作用。Objective:To study the therapeutic mechanism and pharmacodynamic effect of Tiaowei pill.Methods:The chronic bile regurgitational gastritis and acute gastritis in mice were induced by pyloric dilation and filling of bile and small intestinal liquid.The mouse were treated by Tiaowei pill with different doses.Results:Tiaowei pill has the hemorrhage relieving and myxedema analgesia easing on the subject mice effects .Conclusion:On the acute and chronic bile regurgitational gastritis, Tiaowei pill has a better curative effect.

关 键 词：调胃丸 胃炎 胆汁反馈 药理作用 中药 

分 类 号：R286.5[医药卫生—中药学] R285.5[医药卫生—中医学]