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机构地区:[1]天津医科大学生物医学工程系
出 处:《医疗设备信息》2000年第1期6-7,共2页Information of Medical Equipment
摘 要:为了使用线阵CCD高速采集系统直接记录声带振动影像 (即波形 ) ,通过设计取景器克服线阵CCD成像无法实时观察这一困难。To record image of vocal fold vibration with high -speed line scanning CCD of recording system, we design viewfinder to deal with the problem that line scanning CCD real-time imaging can not be observed Connecting viewfinder with laryngoscope, we can record the waveform of vocal fold vibration with high -speed line scanning CCD of recording system Key words: line scanning CCD; vocal fold vibration; viewfindercer by silver staining telomeric repeat amplification protocol$$$$ GU Tao, WANG Xu, LIU Yong, et al (Oncology Institute , Xuzhou Medical College, Xuzhou, Jiangsu 221002, China)Abstract:Objective To study the telomerase activity in lung cancer and identify whether it can be a specific tumor marker or not. Methods Telomerase activity was measured in the specimens of lung cancer tissue, adjacent tissue, normal tissue and lymph nodes from 34 primary lung cancer patients by PCR based silver staining telomeric repeat amplification protocol(TRAP). Control study was made on the specimens taken from 6 patients with benign lung lesions (3 lung cysts and 3 tumorous inflammatory lesions).Results The telomerase activity was positive in 88.3%(30/34) lung cancer specimens,5.8%(2/34) their adjacent tissue specimens and 18.5%(8/28) lymph nodes specimens . No telomerase activity was found in normal tissues. Only 16.7%(1/6) benign lung lesions showed telomerase activity. Conclusion Telomerase activity may be a specific tumor marker in diagnosis of lung cancer. The non-radioisotopic silver staining TRAP, cheap in cost and causing no radio active pollution,is of practical value clinically.
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