群体感应对铜绿假单胞菌生物被膜形成的调控  

Regulation of biofilm formation in Pseudomonas aeruginosa by quorum sensing

作　　者：黄媛媛[1] 宋水山[1] 

机构地区：[1]河北省科学院生物研究所,石家庄050081

出　　处：《生物学杂志》2011年第6期73-76,共4页Journal of Biology

基　　金：国家自然科学基金(NO.30970030);河北省自然科学基金(NO.C2007000960)

摘　　要：生物被膜是一种与浮游细胞相对应的生长方式,由细菌和自身分泌的包外基质组成。铜绿假单胞菌是研究这一生长方式的模式生物。在过去十年,对铜绿假单胞菌生物被膜的研究已取得显著进展。群体感应(QS)的细胞沟通机制在铜绿假单胞菌生物被膜形成中发挥着重要作用。介绍生物被膜的特点,并重点讨论了QS和生物被膜之间的关系。Compared with planktonic cells, bacterial biofilm is a kind of particular colonial life style which consists of bacteria and their extracellular matrix. Pseudomonas aeruginosa has become a model organism for studying biofilm formation. Over the past decade, significant strides have been made towards understanding biofilm development in Pseudomonas aeruginosca Quorum sensing （QS）has been found to play a role in Pseudomonas aeruginosa biofilm formation. This paper introduced the biofilm characteristics,focusing on the relationship between QS and biofilm formation in Pseudomonas aeruginosa biofilm.

关 键 词：群体感应 铜绿假单胞菌 生物被膜 

分 类 号：Q81[生物学—生物工程]