冠状动脉慢性闭塞病变介入治疗的回顾性分析  

Coronary artery occlusion of the chronic disease intervention treatment retrospectively analyzed

作　　者：尹晓姝[1] 洪浪[1] 王洪[1] 尹秋林[1] 李林锋[1] 李彬[1] 黄勤[1] 蔡新勇[1] 

机构地区：[1]江西省人民医院心内二科,南昌330006

出　　处：《江西医药》2011年第11期973-977,共5页Jiangxi Medical Journal

摘　　要：目的观察和分析冠状动脉慢性闭塞病变(chronic total occlusion,CTO)患者的临床和病变特点及介入治疗的效果,提高危重冠心病患者的介入治疗成功率和生存率。方法连续收集2008年10月至2011年10月住院经冠脉造影检查证实冠状动脉慢性闭塞并行经皮冠脉介入治疗(percutaneous coronary intervention,PCI)的患者202例,对患者临床资料、PCI结果、术中术后并发症、心功能和住院期间主要心血管不良事件(major adverse cardiac events,MACE)等进行回顾性分析。结果 202例患者共处理冠状动脉CTO病变272处,成功开通240处,CTO病变的PCI开通率为88.2%(240/272),并发症少,术中无死亡病例,术后住院期间无MACE发生,无患者进行急诊冠状动脉旁路移植术(coronary artery bypass grafting,CABG)。术后心功能(左室射血分数)均较术前有显著的改善,术后心绞痛缓解率100%。结论介入治疗干预CTO病变成功率高,无严重并发症,可改善长期慢性冠状动脉闭塞,提高其生活质量,降低死亡率。Objective To observate and analysis the clinical and pathological characteristics and the effect of interventional treatment of coronary artery disease patients with chronic total occlusion （CTO）lesions ,to improve patients with critical coronary heart disease intervention treatment success rates and survival.Methods Continuously collected from October 2008 to October 2011,202 patients with chronic total occlusion diagnosed by coronary artery angiography and treated with percutaneous coronary intervention （PCI） treatment were enrolled in this study.Clinical data,PCI results,intraoperative and postoperative complications, cardiac function and hospital major adverse cardiac events （MACE） during follow-up were retrospectively analyzed.Results Of the 202 patients, CTO lesions were treated by 272 and successful opening were achieved in 240.The success rate of interventional treatment of CTO lesions was 88.2%（240~272）with a low rate of complications of interventional treatment.No deaths occurred during operation,no MACE oc- curred during postoperative hospitalization and no patients were treated with emergency coronary artery bypass grafting （CABG）.Com- pared with preoperative,cardiac function （left ventricular ejection fraction） was significant improvement,postoperative angina remis- sion rateswere 100%.Conclusion Intervention treatment is safe and feasible intervention CTO lesions,a high success rate,no serious complications and chronic coronary occlusion may improve long-term prognosis of patients, improving quality of life and reduce mortality.

关 键 词：冠状动脉 慢性闭塞病变 介入治疗 回顾性分析 

分 类 号：R541.4[医药卫生—心血管疾病]