云南保山市甲型H1N1流感病毒裂解疫苗应急接种效果分析  

Effectiveness of H1N1 influenza split-virus vaccine in emergency vaccination at Baoshan of Yunnan

作　　者：张安柱[1] 李婉[1] 段生朝[1] 王黎明[1] 林冬梅[1] 马崇惠[1] 段平常[1] 张腾[1] 

机构地区：[1]云南省保山市疾病预防控制中心,678000

出　　处：《首都公共卫生》2011年第6期267-269,共3页Capital Journal of Public Health

摘　　要：目的了解保山市2009～2010年甲型H1N1流感病例的分布特征及疫苗控制效果,为甲型H1N1流感防控及疫苗的科学使用提供依据。方法回顾性分析接种疫苗前后保山市甲型H1N1流感发病人群的分布特征,并比较接种前后甲型H1N1流感发生情况。结果该市总人口接种率为6.26%,其中学生接种率最高为73.44%。甲型H1N1流感实施应急接种疫苗前甲型H1N1流感共计发病68例,发病率为2.77/10万,其中发病最高的是青壮年,实施应急接种后的易感人群发病率低于应急接种前的发病率(P<0.05)。接种甲型H1N1流感疫苗人群总的发病率要低于未接种人群(χ2=4.134,P<0.05)。结论使用甲型H1N1流感病毒裂解疫苗,并根据甲型H1N1流感的流行病学特征对其进行防控,对疫情的控制有较好的效果。Objective To understand distribution characteristics of influenza A/H1N1 cases and effectiveness of influenza A/H1N1 split-virus vaccine during 2009~2010 in Baoshan,Yunnan to provide scientific evidence for its use.Methods Distribution characteristics of influenza A/H1N1 cases during October 2009 to July 2011 before and after vaccination in Baoshan city,Yunnan were analyzed retrospectively.Results Overall coverage of influenza A/H1N1 vaccine in Baoshan was 6.26 percent,the highest in students（73.44%）.In total,68 cases of influenza A/H1N1 occurred in Baoshan before emergency vaccination,with an overall incidence of 2.77 per 100000 population,the highest in young adults and the able-bodied.Overall incidence of influenza A/H1N1 in susceptible population was significantly lower after emergency vaccination than that before it（P0.05）.Incidence of influenza A/H1N1 in inoculated population was significantly lower than that in non-inoculated ones（χ2=4.134,P0.05）.Conclusion Use of influenza A/H1N1 split-virus vaccine is effective for prevention and control of influenza A/H1N1 epidemic in Baoshan.

关 键 词：甲型H1N1流感 流行病学 疫苗效果 

分 类 号：R511.7[医药卫生—内科学]