瑞舒伐他汀钙片与蒲参胶囊降脂疗效比较  

Rosuvastatin Calcium and Pusen capsule lipid-lowering curative effect more

作　　者：邓庆梅[1,2] 

机构地区：[1]大庆龙南医院老年病科 [2]齐齐哈尔医学院第五附属医院老年病科,黑龙江大庆163453

出　　处：《中国伤残医学》2011年第12期21-23,共3页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:观察瑞舒伐他汀钙片与蒲参胶囊降脂效果差别。方法:将确诊的高血脂患者随机分为2组:瑞舒伐他汀组42例,每晚服瑞舒伐他汀钙10mg;蒲参胶囊,每次4粒,每日3次;疗程8周。比较2组降脂效果,同时观察治疗期间不良事件。结果:2组治疗前后血脂水平变化比较与同组治疗前相比,治疗后TC、TG、LDL-C均有明显下降(P<0.05),HDL—C明显升高(P<0.05)。2组治疗8周后总有效率比较,TC、LDL-C总有效率瑞舒伐他汀组优于蒲参胶囊组,TG总有效率蒲参胶囊组优于瑞舒伐他汀组,有明显差异(P<0.05);HDL—C总有效率2组无明显差异(P>0.05).治疗期间2组不良反应均轻微。结论:瑞舒伐他汀对TC,LDL-C降低优于蒲参胶囊,蒲参胶囊对于TG的降低疗效优于瑞舒伐他汀钙片。Objective：To observe Rosuvastatin Calcium and Pusen capsule lipid-lowering effect difference. Methods：Will be diagnosed high blood fat patients were randomly divided into two groups：Rosuvastatin Calcium group were 42 patients,Take Rosuvastatin Calcium 10 mg per night; Pusen capsule,Every time 4 grain, 3 times a day; Course of 8 weeks. Compare two sets of reduced fat effect, and observed during treatment adverse events. Results：Two groups before and after treatment change is lipid levels before treatment, compared with your group.After treatment, the TC, TG, LDL-C were significantly down（P0.05）,H DL-C increased significantly （P0.05）. Two groups of treatment after eight weeks, the total effective rate compared,TC, LDL-C total effective Rosuvastatin Calcium group was higher than the Pusen capsule group,TG total effective the Pusen capsule group was higher than Rosuvastatin Calcium group,and there is a distinct difference （P0.05）. HDL-C total effective rate no difference between the two groups （P0.05）. During treatment, two groups of adverse reactions are minimal.Conclusions：Rosuvastatin Calcium of TC, LDL-C reduce might be better than Pusen capsule,.Pusen capsule for the better therapeutic TG reduce Rosuvastatin Calcium.

关 键 词：瑞舒伐他汀钙片 蒲参胶囊 降脂 

分 类 号：R917[医药卫生—药物分析学]