生物光子与藏药七十味珍珠丸的药理机制  

Biophotons are Involved in the Pharmacological Mechanisms of Ratnasampil

作　　者：孙燕[1,2] 冯斌[1] 龙运然[2] 戴甲培[1,2] 

机构地区：[1]中南民族大学武汉神经科学和神经工程研究所,武汉430074 [2]中南民族大学药学院,武汉430074

出　　处：《中南民族大学学报（自然科学版）》2011年第4期53-58,共6页Journal of South-Central University for Nationalities：Natural Science Edition

基　　金：中央高校基本科研业务费专项资金资助项目(ZZY10011);中南民族大学重点科研机构基金(XJS09001)

摘　　要：采用高度敏感的生物光子检测(成像)系统(主要由电子倍增CCD和体视显微镜组成),研究了藏药七十味珍珠丸(RNSP)灌胃处理对健康成年雌性昆明小鼠脑片、肝和肾组织的生物光子活动调控的影响.实验结果表明:脑片、肝和肾均具有自发光现象(生物光子).在光刺激下,脑片、肝和肾具有不同程度的诱发光现象.RNSP处理后的脑组织诱发光的最大值高于对照组,并且衰减较慢.研究结果提示RNSP可能通过影响效应组织如脑组织的生物光子的活动来发挥其药理作用.其作用机制可能是通过影响生物光子信号传递对组织细胞功能产生调节作用,确切的作用机制值得进一步研究.A highly sensitive biophoton detection （imaging） system （ mainly consisting of an Electron multiplying CCD and a stereoscope） was utilized to detect the biophoton activities in adult female Kunming mice treated with Ratnasampil （RNSP） （ig）. Ten days after RNSP treatment, the effects of RNSP on the changes of biophoton emission from the isolated brain slices, liver and kidney samples were investigated. Experimental results showed that the brain slices, liver and kidney can emit spontaneous uhraweak photons, which were more intensive after light illumination. The maximum values of induced photon emission of the brain slices were higher in RNSP treated group than that in control group, and the decay was slower. These results suggest that the pharmacological effect of RNSP may take place by influencing the biophotonic activities in the target tissues such as the brain. The possible mechanism may be that RNSP regulates the functions of tissue cells by influence of biophoton signal communications, although the exact mechanisms need to be investigated further.

关 键 词：生物光子 电子倍增CCD 藏药七十味珍珠丸 

分 类 号：Q633[生物学—生物物理学] R912[医药卫生—药学]