质子酸催化紫苏葶脱肟反应的研究  

Study on Bronsted Acid-Catalyzed Deoximation of Perillartine

作　　者：李谦和[1] 欧阳美凤[1] 肖利民[1] 周旺[1] 

机构地区：[1]湖南师范大学精细催化合成研究所,中国长沙410081

出　　处：《湖南师范大学自然科学学报》2011年第6期45-48,共4页Journal of Natural Science of Hunan Normal University

基　　金：国家自然科学基金资助项目(200146001;20206010)

摘　　要：研究了质子酸催化紫苏葶脱肟制备紫苏醛的反应,反应的实质是紫苏葶与甲醛在酸催化下的交换反应.考察了反应条件对紫苏葶转化率和紫苏醛产率的影响,研究结果表明:用硝酸作催化剂时,在硝基甲烷溶剂中,以紫苏葶与甲醛于80℃反应4 h,紫苏葶转化率可达96.2%,紫苏醛的选择性为100%,为高纯度紫苏醛的合成提供了一条便捷的途径.Synthesis of perillaldehyde by acid-catalyzed exchange reaction between perillartine and formaldehyde was studied. The influence of reaction variables was evaluated. The results showed that 96.2% conversion of perillartine and 100% selectivity of the product were obtained in the presence of nitric acid as catalyst at 80 ℃ for 4 h in nitromethane. It provides a convenient way for the preparation of highly pure perilaldehyde.

关 键 词：紫苏葶 酸催化 脱肟 紫苏醛 

分 类 号：O621.25[理学—有机化学] O643.32[理学—化学]