自体CIK细胞治疗恶性肿瘤的护理  

Nursing care for malignant tumour patients treated with autologous CIK cells

作　　者：王茜[1] 张月桂[2] 黄孙卉[2] 卢珊[1] 李凤琴[1] 

机构地区：[1]哈尔滨医科大学附属第三医院内八科,哈尔滨150081 [2]哈尔滨医科大学肿瘤防治研究所

出　　处：《实用肿瘤学杂志》2011年第6期561-563,共3页Practical Oncology Journal

摘　　要：目的 观察73例恶性肿瘤患者进行CIK细胞治疗后的反应及护理体会.方法 73例恶性肿瘤患者使用血细胞分离机采集外周血单个核细胞（PBMC）,在体外诱导扩增CIK细胞后给予静脉回输,观察其疗效及不良反应.结果 本组51例患者反馈睡眠质量、食欲、活动耐力、精神状态有不同程度改善,22例患者未见明显改善;除3例出现低热反应外,其余无不良反应发生.结论 CIK细胞治疗是一种安全有效的治疗方法,对患者伤害小,不良反应少,经护理干预,可改善恶性肿瘤患者的生存质量,在过继性免疫治疗中具有良好的应用前景.Objective To study the feedback and attentance experiences in 73 malignant tumor patients treated with CIK （ cytokine induced killer） cells. Method Peripheral blood mononuclear cell （ PBMC ） from 73 malignant tumor patients were separated and gathered by blood corpuscle separate machine. The PBMC were cultured and proliferate in vitro and finally transfused back to these patients. The therapeutic effects were evaluated, and the adverse reaction were investigated. Results The sleep quality, appetite, stamina, and mental status were improved in 51 patients with different degrees, while no significantly improvement was observed in the rest patients;Except three patients （4.1% ）observed with low - grade fever reactions, adverse effect was not found in all other cases（95.9% ）. Conclusion The CIK cells therapy is a safe,effective and feasible approach with few adverse effects for treatment malignant tumor patients, and the living quality of patients can be improved with the nursing interference. Therefore, the CIK cell therapy may have good application prospects in adoptive immunotherapy of cancer.

关 键 词：CIK细胞 恶性肿瘤 护理 

分 类 号：R473.73[医药卫生—护理学]