手足口病患儿血清心肌酶谱检测的临床意义  

Clinical significance of detecting myocardial enzymes in serum of children with hand foot and mouth disease

作　　者：胡淑琴[1] 王绪韶[1] 冷建武[1] 姜开军[1] 刘志远[1] 孙景巍[1] 

机构地区：[1]安徽省蚌埠市第一人民医院儿科,233000

出　　处：《临床合理用药杂志》2011年第23期45-46,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨手足口病(HFMD)患儿血清中心肌酶谱变化的临床意义。方法将98例手足口病患儿作为观察组,另选健康体检儿童20例作为对照组。检测2组患儿空腹血清中天冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)。结果观察组患儿心肌酶谱异常率分别为AST28.0%、LDH72.8%、CK43.8%、CK-MB38.6%,其含量均明显高于对照组(P<0.01)。结论测定血清心肌酶谱能及时了解手足口病患儿心肌损害程度,对临床诊治及预后判断具有重要意义。Objective To explore the clinical significance of detecting myocardial enzymes in serum of children with hand foot and mouth disease（HFMD）. Methods 98 cases HFMD children as observation group and 20 cases healthy children as control group. Detected the fasting serum aspartate aminotransferase （AST）, lactate dehydrogenase （LDH）, creatine kinase （ CK）, creatine kinase isoenzyme （CK-MB）. Results Observation group of serum myocardial enzymes in children with abnormal rate were AST 28.0%, LDH 72.8%, CK 43.8%, CK-MB 38.6%, contents were significantly higher than those in control group （ P 〈 0.01 ）. Conclusion Serum myocardial enzymes can keep abreast of children with HFMD myocardial damage, treatment and prognosis of clinical significance.

关 键 词：手足口病 心肌酶谱 心肌损害 

分 类 号：R725.1[医药卫生—儿科]