夏天无提取工艺优化  

Optimization of Extract Technology of Corydalis decumbens by Orthogonal Experiment

作　　者：桂婵[1] 吴安明 何雁[1] 黄恺 傅亮[1] 徐兰[1] 罗晓健[1,3] 

机构地区：[1]江西中医学院,南昌330006 [2]江西天施康中药股份有限公司,江西鹰潭335000 [3]中药固体制剂国家工程中心,南昌330006

出　　处：《中国实验方剂学杂志》2012年第1期4-7,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：科技人员服务企业行动项目(2009GJC50010)

摘　　要：目的:优选夏天无的最佳提取工艺。方法:以毕枯枯林等4个药效指标成分含量和浸膏得率为考察指标,采用正交设计试验优化提取工艺,采用相关性检验和综合平衡法优选最佳提取工艺。结果:最佳提取工艺为加入11倍量70%乙醇回流提取3次,每次2.5 h。结论:优选的提取工艺稳定可行,能够较好保留药效成分。Objective：To optimize extraction process of Corydalis decumbens.Method：The content of bicuculline,protopine,tetrahydropalmatine,palmatine and yield of extract as indexes,optimization of extract technology by orthogonal experiment and correlation test and comprehensive balance method.Result：Optimum extraction condition was as follows：refluxing extracted 3 times with 11 times the amount of 70% ethanol by 2.5 h each time.Conclusion：This optimum technology was stable and feasible,it could keep effective components better.

关 键 词：夏天无 毕枯枯林 原阿片碱 延胡索乙素 巴马汀 正交试验 

分 类 号：R283.6[医药卫生—中药学]