辽宁省五味子木脂素含量动态变化研究  

Research on Dynamic Change of Lignanoid Content of Fructus Schisandrae in Liaoning Province

作　　者：李先宽[1] 王冰[1] 何华[1] 韩荣春[1] 

机构地区：[1]辽宁中医药大学,辽宁大连116600

出　　处：《中国实验方剂学杂志》2012年第1期107-112,共6页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：辽宁省教育厅项目(LT2010067);科技基础性工作专项重点项目(2007FY110600)

摘　　要：目的:对辽宁省不同产地、不同生长期的野生种和栽培种五味子果实木脂素含量动态变化进行研究。方法:采用反相高效液相色谱法对五味子果实木脂素类指标成分含量进行分析。结果:不同生长期的五味子果实,5种木脂素类指标成分含量,除栽培种中的五味子酯甲和平原地区栽培种中的五味子甲素外,其他指标成分及5种指标成分总含量,均随生长期延长而逐渐升高,在半成熟期时含量达最高值;五味子果实进入成熟期后,除平原地区栽培种中的五味子酯甲和五味子甲素外,其他木脂素类指标性成分含量与半成熟期含量相比均有不同幅度降低。结论:辽宁省栽培种五味子果实其5种指标性成分在一个生长周期内含量动态变化与野生种相似。Objective：Research on dynamic change of the lignanoid content of Fructus Schisandrae fruits between different regions,growth periods,wild species and cultivated species in Liaoning province.Method：RP-HPLC method was applied to compare the index ingredients quantities of lignanoid in Fructus Schisandrae fruits.Result：In addition to the schisantherin A of cultivated species and the deoxyschisandrin of cultivated species in plain,in different growth periods other index ingredients and the overall 5 lignanoids content gradually elevated corresponding to the elongation of the growth periods and reached their peak at semi-maturation phase;comparing to semi-maturation phase,the index ingredients of Fructus Schisandrae fruits except the schisantherin A and the deoxyschisandrin of cultivated species in plain in their maturation phase decreased.Conclusion：The dynamic change of the index ingredients quantities of the cultivated Fructus Schisandrae fruits was familiar to that of the wild species in Liaoning province.

关 键 词：五味子 木脂素含量 生长周期 动态变化 

分 类 号：R284.1[医药卫生—中药学]