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机构地区:[1]广州市中医医院,广州510130 [2]广州中医药大学第一附属医院,广州510405
出 处:《中国实验方剂学杂志》2012年第1期220-222,共3页Chinese Journal of Experimental Traditional Medical Formulae
摘 要:目的:观察疏肝活血明目汤联合甲强龙冲击治疗急性视神经乳头炎的临床疗效。方法:将50例(54眼)急性视神经乳头炎患者随机分为治疗组和对照组,对照组给予甲强龙(1 000 mg,1次/d,连用3 d后减量)和一般辅助治疗,治疗组在此基础上加用自拟疏肝活血明目汤每日1剂,1个月为1个疗程,共观察2个疗程。观察治疗前后2组患者的视力、眼底、视野等的变化。结果:治疗组总有效率为100%,对照组总有效率为92%,2组之间的差别有统计学意义(P<0.05)。治疗组在视力、视野、眼底等方面的改变均优于对照组。结论:疏肝活血明目汤联合甲强龙冲击治疗能够显著改善急性视神经乳头炎患者的临床症状,提高视力,降低视野平均阈值敏感度,减轻视乳头的充血、水肿,促进视网膜出血的吸收。Objective:To observe clinical efficiency of Shugan Huoxue Mingmu decocotion combined with methylprednisolone pulse therapy.on acute optic neuritis(AON).Method:Fifty patients(54 eyes) with AON were randomly divided into treatment group and control group.All patients were given methylprednisol impacting and the general adjuvant therapy.The treatment group was given Shugan Huoxue Mingmu decocotion.The treatment course was 1 month,and the clinical observation lasted two courses.Before and after treatment,visual acuity,fundus,visual field and other changes were observed.Result:The total effective rate was 100% in the treatment group and 92.0% in the control group,and there was a statistically significant difference(P〈0.05).The changes in visual acuity,fundus,visual field of the treatment group were improved compared with control group.Conclusion:Shugan Huoxue Mingmu decocotion combined with methylprednisolone can significantly improve clinical symptoms of AON patients and increase visual acuity,reduce the average threshold sensitivity of vision,the optic nerve edema and promote the absorption of retinal hemorrhage.
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