补阳还五汤治疗2型糖尿病研究进展  

Research and Development for Buyang Huanwu Tang in Treating Type 2 Diabetes

作　　者：张林军[1] 刘军[1] 常超[2] 封利广 常风云[4] 

机构地区：[1]河北体育学院人体科学系,石家庄050061 [2]邯郸市第一医院,河北邯郸056002 [3]河北省鹿泉市李村中心卫生院,河北鹿泉050223 [4]河北医科大学中西医结合学院,石家庄050091

出　　处：《中国实验方剂学杂志》2012年第1期243-246,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：对补阳还五汤治疗2型糖尿病及合并症的现状进行文献整理和分析。以补阳还五汤和糖尿病为主题词对CNKI和万方数据自1979年以来的文献进行检索,对检索的350余篇相关文献就益气活血法治疗糖尿病的历史沿革、临床应用和动物实验进行了归纳分析。气虚血瘀是糖尿病的主要病因病机之一。补阳还五汤临床治疗糖尿病及合并症疗效满意的原因是抓住了气虚血瘀这一主要矛盾。如病机以肾阳不足/阴虚燥热等为主要矛盾时,应据证另选良方,否则不顾病机而名方滥投亦难取效。动物实验从分子水平初步揭示了补阳还五汤治疗糖尿病及合并症的机制,但在基因水平的研究还有待深入,今后应注重该方治疗糖尿病作用环节/靶点的研究,深入研究该方治疗糖尿病的有效成分及提取方法,为研制治疗糖尿病新药奠定理论基础。The diabetes complications and rearrange and analysis Buyang Huanwu Tang in the treating II Diabetes.To Buyang Huanwu Tang and diabetes and ten thousand to give priority to captioned CNKI the data from 1979 the literature retrieval.Of the 350 papers to retrieval ofliterature and blood-activation therapy for diabetes history,clinical application and animalexperiments are analyzed.Qi difficiency and blood stasis are the main causes and mechanism of diabetes.Buyang Huanwu Tang soup in the treatment of diabetes complications and clinical results were satisfactory reason is caught qi difficiency and blood stasis the main contradiction.If kidney Yang deficiency in pathogenesis or Yin scorching as the main contradiction,should according to card swap cures,regardless of the pathogenesis and square or bad shots take effect also difficult.Animal experiments from molecular level initially revealed Buyang Huanwu Tang soup in the treatment of diabetes and the mechanism of complications.,But in the level of gene are to be further discussed.We should pay attention to his own in the treatment of diabetes link or targets of research,deep inside his own research in the treatment of diabetes of the effective components and extraction method,developed new drugs for the treatment of diabetes theoretical basis.

关 键 词：补阳还五汤 Ⅱ型糖尿病 气虚血瘀 

分 类 号：R287[医药卫生—中药学]