2型糖尿病患者合并微血管病变的危险因素分析  

Analyze risk factors of type 2 diabetic patients with Microangiopathy

作　　者：吴艳[1] 徐志刚[1] 王秀华[1] 

机构地区：[1]江苏省镇江市第一人民医院内分泌科,镇江212000

出　　处：《北方药学》2012年第1期64-65,共2页Journal of North Pharmacy

摘　　要：目的:了解糖尿病微血管病变发生的危险因素,为预防和干预糖尿病微血管病变的发生提供科学依据。方法:对2009年7月收集的江苏地区2966例2型糖尿病(T2DM)患者进行回顾性分析,合并微血管病变组(A组)、无微血管病变组(B组),检测其17个相关临床指标及一般资料,并对其进行Logistic多因素回归分析。结果:两组年龄、病程、HbA1c、餐后血糖、高密度脂蛋白胆固醇、收缩压、血肌酐、尿酸、患者来源及家庭平均月收入构成差异,有统计学意义(P<0.05),但仅HbA1c、收缩压、病程与微血管病变发生呈显著正相关(P<0.05)。结论:高血糖、高血压、高血脂是2型糖尿病患者微血管病变发生的危险因素。糖尿病患者自身对糖尿病的认识和配合,对于促进患者血糖达标也非常重要。Objective： To determine of diabetic mierovascular disease risk factors,provide the scientific basis for Intervention and prevention of incidence of diabetic mieroangiopathy.Methods：We conducted retrospective analysis on 2966 patients with type 2 diabetes mellitus collected during July 2009 in Jiangsu province.Mark A and B with patients combined mieroangiopathy and uncombined mieroangiopathy, respectively. Detect 17 relevant clinical indicators and general Information, conduct retrospective analysis on these index. Results： Age, duration of diabetes, HbAle, postprandial blood glucose, High-density lipoprotein cholesterol, systolic blood pressure,blood creatinine, blood uric acid, source of patients, average monthly household income revealed difference between two groups of patients （P〈0.05）. Incidence of diabetic microangiopathy was positively related to HbAle,systolic blood pressure, duration of diabetes（P〈0.05 ）.Conclusions： Hyperglycemia, hypertension, high cholesterol were risk factors of the incidence of diabetic microangiopathy.Diabetes self-awareness of diabetes and co for the promotion of patient blood glucose is also very important.

关 键 词：糖尿病微血管病变 2型糖尿病 危险因素 

分 类 号：R587.1[医药卫生—内分泌]