1019例门诊静脉输液儿童药物不良反应报告分析  

Analysis of 1019 Adverse Drug Reaction Reports in Children through Intravenous Infusion in Outpatient Department

作　　者：郭鹏飞[1] 赵平[1] 

机构地区：[1]重庆医科大学附属儿童医院,重庆400014

出　　处：《儿科药学杂志》2012年第1期31-33,共3页Journal of Pediatric Pharmacy

摘　　要：目的:了解我院门诊静脉输液儿童药物不良反应(ADR)发生情况,为临床合理用药提供参考。方法:采用回顾性调查分析方法,对2009年1月1日～2010年12月31日我院门诊1 019例ADR患儿的报告资料进行统计分析。结果:门诊静脉输液儿童ADR发生率为1.2‰,以1～3岁小儿最多;药物中以抗微生物药居首位,占69.4%,其次为中药注射剂,占26.7%;ADR临床表现以皮肤及附件损害最常见,占79.6%。结论:门诊静脉输液儿童ADR发生率高,应加强儿童ADR监测,尽可能减少门诊儿童静脉用药,避免或减少ADR发生。Objective： To fathom the occurrences of adverse drug reaction（ADR） of children through intravenous infusion in outpatient department of our hospital and to guide rational drug use.Methods： We retrospectively analyzed the 1,019 ADR reports in our hospital from January 1st,2009 to December 31st,2010.Results： The ADR incidence rate of these children was about 1.2‰.Most ADR occurred in young children from one to three years old.The 1,019 ADR reports were related to 40 kinds of drugs,of which 707 ADR were related to anti-infectious drugs,accounting for 69.4%;272 ADR were related to traditional Chinese medicine injection,accounting for 26.7%.The clinical manifestation of most ADR was skin lesion,accounting for 79.6%.Conclusions： The ADR incidence rate of these children was high.Supervision of the ADR should be strengthened,as much as possible to decrease intravenous infusion and to avoid or reduce ADR incidence.

关 键 词：药物不良反应 儿童 门诊 静脉输液 

分 类 号：R725.953[医药卫生—儿科]