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作 者:杨廷桂[1] 王冬梅[1] 周根来[1] 方希修[1] 齐富刚[1] 王寿轩[2] 朱本康[2]
机构地区:[1]江苏畜牧兽医职业技术学院,山东泰州225300 [2]徐州金牌药业有限公司,江苏徐州221600
出 处:《安徽农业科学》2012年第1期208-209,212,共3页Journal of Anhui Agricultural Sciences
摘 要:[目的]应用"仔猪腹泻康"新兽药对80头仔猪的黄痢进行临床疗效试验,为推广新兽药提供科学依据。[方法]将自然感染确诊为仔猪黄痢的病猪80头随机分为4组,每组20头。药物的高、中、低剂量组分别每头灌服5.0、3.5、2.0 g"仔猪腹泻康",药物对照组灌服3.5 g白头翁散,每天2次,连续3 d。给药后每天观察病猪,记录精神、食欲和下痢情况,观察至停药后第7天统计疗效;分别于给药前和停药后第2天采集血样测定血红蛋白(Hb)、红细胞(RBC)总数、白细胞(WBC)总数的变化。[结果]"仔猪腹泻康"高、中剂量组的治愈率分别为95%、85%,显著高于药物对照组(70%)和药物低剂量组。药物高、中剂量组的病猪数迅速减少,症状迅速减轻,高剂量组的治愈率和总有效率最高,治疗后各组Hb含量和RBC总数有所升高、WBC有所降低,但无显著性差异(P>0.05)。[结论]"仔猪腹泻康"高、中剂量组对仔猪黄痢有较好的疗效,推荐中剂量(3.5 g/头)为临床应用剂量。[Objective] In order to provide the scientific basis,the curative effect of Zizhufuxiekang was observed for 80 clinical piglets with diarrhea dysentery.[Method] 80 piglets yellow scours of natural infection were selected and divided into four groups randomly,each group 20.The high,middle and low-dose drugs group were fed 5 g,3.5 g,2 g Zizhufuxiekang orally respectively,the control drug group was fed 3.5 g Baitouwengsan,2 times a day,3 d.The spirit,appetite and diarrhea cases of pigs were observed after stopping drug until 7 days;the total number of blood hemoglobin(Hb),red blood cell(RBC),white blood cell(WBC) was determined before medication and stopping medication after 2 days respectively.[Result] The cure rates of high-dose drugs group and middle-dose drugs group of Zizhufuxiekang was 95%,85% respectively,it is higher significantly than control drugs group(70%) and low-dose drugs group.The number of disease of pigs in high-dose drugs group and middle-dose drugs group decreased rapidly and symptoms reduced quickly.The cure rate and total effective treatment of high-dose drugs group is the highest.The Hb levels and RBC levels in high-dose drugs group and middle-dose drugs group were increased,and the WBC levels was decreased,but no significant difference(P〉0.05).[Conclusion] It had good treatment of high-dose drugs group and middle-dose drugs group of Zizhufuxiekang in piglet yellow scours,the dose(3.5 g/head) for clinical application was recommended.
分 类 号:S851.3[农业科学—预防兽医学]
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