湛江市褐家鼠对杀鼠灵的抗药性调查  

Resistance of Rattus norvegicus to warfarin in Zhanjiang

作　　者：高志祥[1] 邱俊荣[1] 林伟松[1] 冯志勇[1] 姚丹丹[1] 隋晶晶[1] 

机构地区：[1]广东省农业科学院植物保护研究所,广东广州510640

出　　处：《中国媒介生物学及控制杂志》2011年第6期535-537,共3页Chinese Journal of Vector Biology and Control

基　　金：广东省自然科学基金(8151064001000001);广东省突发公共事件应急技术研究中心项目(2008B080701044);农业公益性行业专项基金(200903004-01);广东省教育部产学研结合项目(2009B090300296)~~

摘　　要：目的检测采自广东省湛江市区的褐家鼠对第一代抗凝血灭鼠剂的抗性发生水平。方法将捕自湛江市的褐家鼠在室内预试验一段时间后,对合格试鼠采用无选择性摄食试验法以0.005%杀鼠灵毒饵饲毒(LFP法),观察并分析试鼠的死亡率与食毒量的关系。结果本次褐家鼠抗性检测合格试鼠计37只,检测结束后试鼠因药物死亡29只,试鼠对杀鼠灵的抗性发生率为21.62%,已经形成抗性种群;死亡试鼠性别间在致死剂量和死亡时间上差异均无统计学意义(P>0.05);全部死亡试鼠平均食毒剂量为(19.14±5.44)mg/kg,平均死亡时间(7.34±3.51)d。结论湛江市区的褐家鼠防治应选用第一代抗凝血灭鼠剂以外的药物,同时注意监测害鼠对药物的敏感度变化,以节省有限的药物资源。Objective To investigate the resistance of Rattus norvegicus to the first-generation rodenticide, warfarin, in Zhanjiang, Guangdong. Methods Rats sampled from the urban areas were screened with a trial test indoor for non-selective feeding with baits containing 0.005% warfarin to observe the dose-response relationship. Results Among 37 eligible candidates for the resistance test, 29 were dead due to administration. The resistance of R. norvegicus was 21.62%, indicating the formation of a resistant community. There was no significant difference in the lethal dose and time between male and female rats （P〉0.05）. The average intake of poison baits was 19.14±5.44 mg/kg, and the average time to death 7.34±3.51 days. Conclusion The first-generation rodenticide was no longer an agent of choice for control of R. norvegicus in Zhanjiang. Monitoring the changes in the resistance among rodent population was necessary for optimal allocation of resources.

关 键 词：褐家鼠 杀鼠灵 抗药性 

分 类 号：S443[农业科学—农业昆虫与害虫防治] S481.4[农业科学—植物保护]